# $Id: neighbor.pm,v 1.5 2003/06/11 17:05:26 letondal Exp $
# BioPerl module for Bio::Tools::Run::PiseApplication::neighbor
#
# Cared for by Catherine Letondal <letondal@pasteur.fr>
#
# For copyright and disclaimer see below.
#
# POD documentation - main docs before the code

=head1 NAME

Bio::Tools::Run::PiseApplication::neighbor

=head1 SYNOPSIS

  #

=head1 DESCRIPTION

Bio::Tools::Run::PiseApplication::neighbor

      Bioperl class for:

	Phylip	neighbor - Neighbor-Joining and UPGMA methods (Felsenstein)

	References:

		Felsenstein, J.  1993.  PHYLIP (Phylogeny Inference Package) version 3.5c. Distributed by the author.  Department of Genetics, University of Washington, Seattle.

		Felsenstein, J.  1989.  PHYLIP -- Phylogeny Inference Package (Version 3.2). Cladistics  5: 164-166.



      Parameters: 

        (see also:
          http://bioweb.pasteur.fr/seqanal/interfaces/neighbor.html 
         for available values):


		neighbor (String)

		distance_method (Excl)
			Distance method

		infile (InFile)
			Distances matrix File
			pipe: phylip_dist

		jumble (Switch)
			Randomize (jumble) input order (J)

		jumble_seed (Integer)
			Random number seed for jumble (must be odd)

		multiple_dataset (Switch)
			Analyze multiple data sets (M)

		datasets_nb (Integer)
			How many data sets

		multiple_seed (Integer)
			Random number seed for multiple dataset (must be odd)

		consense (Switch)
			Compute a consensus tree

		consense_confirm (String)

		consense_terminal_type (String)

		print_tree (Switch)
			Print out tree (3)

		print_treefile (Switch)
			Write out trees onto tree file (4)

		indent_tree (Switch)
			Indent treefile

		printdata (Switch)
			Print out the data at start of run (1)

		outgroup (Integer)
			Outgroup species (default, use as outgroup species 1) (O)

		triangular (Excl)
			Matrix format

		confirm (String)

		terminal_type (String)

=head1 FEEDBACK

=head2 Mailing Lists

User feedback is an integral part of the evolution of this and other
Bioperl modules. Send your comments and suggestions preferably to
the Bioperl mailing list.  Your participation is much appreciated.

  bioperl-l@bioperl.org              - General discussion
  http://bioperl.org/MailList.shtml  - About the mailing lists

=head2 Reporting Bugs

Report bugs to the Bioperl bug tracking system to help us keep track
of the bugs and their resolution. Bug reports can be submitted via
email or the web:

  bioperl-bugs@bioperl.org
  http://bioperl.org/bioperl-bugs/

=head1 AUTHOR

Catherine Letondal (letondal@pasteur.fr)

=head1 COPYRIGHT

Copyright (C) 2003 Institut Pasteur & Catherine Letondal.
All Rights Reserved.

This module is free software; you can redistribute it and/or modify
it under the same terms as Perl itself.

=head1 DISCLAIMER

This software is provided "as is" without warranty of any kind.

=head1 SEE ALSO

=over

=item *

http://bioweb.pasteur.fr/seqanal/interfaces/neighbor.html

=item *

Bio::Tools::Run::PiseApplication

=item *

Bio::Tools::Run::AnalysisFactory::Pise

=item *

Bio::Tools::Run::PiseJob

=back

=cut

#'
package Bio::Tools::Run::PiseApplication::neighbor;

use vars qw(@ISA);
use strict;
use Bio::Tools::Run::PiseApplication;

@ISA = qw(Bio::Tools::Run::PiseApplication);

=head2 new

 Title   : new()
 Usage   : my $neighbor = Bio::Tools::Run::PiseApplication::neighbor->new($location, $email, @params);
 Function: Creates a Bio::Tools::Run::PiseApplication::neighbor object.
           This method should not be used directly, but rather by 
           a Bio::Tools::Run::AnalysisFactory::Pise instance.
           my $factory = Bio::Tools::Run::AnalysisFactory::Pise->new();
           my $neighbor = $factory->program('neighbor');
 Example : -
 Returns : An instance of Bio::Tools::Run::PiseApplication::neighbor.

=cut

sub new {
    my ($class, $location, $email, @params) = @_;
    my $self = $class->SUPER::new($location, $email);

# -- begin of definitions extracted from /local/gensoft/lib/Pise/5.a/PerlDef/neighbor.pm

    $self->{COMMAND}   = "neighbor";
    $self->{VERSION}   = "5.a";
    $self->{TITLE}   = "Phylip";

    $self->{DESCRIPTION}   = "neighbor - Neighbor-Joining and UPGMA methods";

    $self->{OPT_EMAIL}   = 0;

    $self->{AUTHORS}   = "Felsenstein";

    $self->{DOCLINK}   = "http://bioweb.pasteur.fr/docs/gensoft-evol.html#PHYLIP";

    $self->{REFERENCE}   = [

         "Felsenstein, J.  1993.  PHYLIP (Phylogeny Inference Package) version 3.5c. Distributed by the author.  Department of Genetics, University of Washington, Seattle.",

         "Felsenstein, J.  1989.  PHYLIP -- Phylogeny Inference Package (Version 3.2). Cladistics  5: 164-166.",
 ];

    $self->{_INTERFACE_STANDOUT} = undef;
    $self->{_STANDOUT_FILE} = undef;

    $self->{TOP_PARAMETERS}  = [ 
	"neighbor",
	"distance_method",
	"infile",
	"jumble_opt",
	"bootstrap",
	"consense_confirm",
	"consense_terminal_type",
	"consense_outfile",
	"consense_treefile",
	"output",
	"other_options",
	"outfile",
	"treefile",
	"indented_treefile",
	"params",
	"confirm",
	"terminal_type",
	"tmp_params",

    ];

    $self->{PARAMETERS_ORDER}  = [
	"neighbor",
	"distance_method", 	# Distance method
	"infile", 	# Distances matrix File
	"jumble_opt", 	# Randomize options
	"jumble", 	# Randomize (jumble) input order (J)
	"jumble_seed", 	# Random number seed for jumble (must be odd)
	"bootstrap", 	# Bootstrap options
	"multiple_dataset", 	# Analyze multiple data sets (M)
	"datasets_nb", 	# How many data sets
	"multiple_seed", 	# Random number seed for multiple dataset (must be odd)
	"consense", 	# Compute a consensus tree
	"consense_confirm",
	"consense_terminal_type",
	"consense_outfile",
	"consense_treefile",
	"output", 	# Output options
	"print_tree", 	# Print out tree (3)
	"print_treefile", 	# Write out trees onto tree file (4)
	"indent_tree", 	# Indent treefile
	"printdata", 	# Print out the data at start of run (1)
	"other_options", 	# Other options
	"outgroup", 	# Outgroup species (default, use as outgroup species 1) (O)
	"triangular", 	# Matrix format
	"outfile",
	"treefile",
	"indented_treefile",
	"params",
	"confirm",
	"terminal_type",
	"tmp_params",

    ];

    $self->{TYPE}  = {
	"neighbor" => 'String',
	"distance_method" => 'Excl',
	"infile" => 'InFile',
	"jumble_opt" => 'Paragraph',
	"jumble" => 'Switch',
	"jumble_seed" => 'Integer',
	"bootstrap" => 'Paragraph',
	"multiple_dataset" => 'Switch',
	"datasets_nb" => 'Integer',
	"multiple_seed" => 'Integer',
	"consense" => 'Switch',
	"consense_confirm" => 'String',
	"consense_terminal_type" => 'String',
	"consense_outfile" => 'Results',
	"consense_treefile" => 'Results',
	"output" => 'Paragraph',
	"print_tree" => 'Switch',
	"print_treefile" => 'Switch',
	"indent_tree" => 'Switch',
	"printdata" => 'Switch',
	"other_options" => 'Paragraph',
	"outgroup" => 'Integer',
	"triangular" => 'Excl',
	"outfile" => 'Results',
	"treefile" => 'Results',
	"indented_treefile" => 'Results',
	"params" => 'Results',
	"confirm" => 'String',
	"terminal_type" => 'String',
	"tmp_params" => 'Results',

    };

    $self->{FORMAT}  = {
	"neighbor" => {
		"perl" => '"neighbor < params"',
	},
	"distance_method" => {
		"perl" => '($value eq "upgma") ? "N\\n" : ""',
	},
	"infile" => {
		"perl" => '"ln -sf $infile infile; "',
	},
	"jumble_opt" => {
	},
	"jumble" => {
		"perl" => '($value) ? "J\\n$jumble_seed\\n" : ""',
	},
	"jumble_seed" => {
		"perl" => '""',
	},
	"bootstrap" => {
	},
	"multiple_dataset" => {
		"perl" => '($value) ? "M\\n$datasets_nb\\n$multiple_seed\\n" : ""',
	},
	"datasets_nb" => {
		"perl" => '""',
	},
	"multiple_seed" => {
		"perl" => '""',
	},
	"consense" => {
		"perl" => '($value)? "; cp infile infile.neighbor; cp outtree outtree.neighbor; mv outfile outfile.neighbor; mv outtree intree; consense < consense.params; cp outtree outtree.consense; cp outfile outfile.consense; mv outtree.neighbor outtree; mv infile.neighbor infile; mv outfile.neighbor outfile" : ""',
	},
	"consense_confirm" => {
		"perl" => '"Y\\n"',
	},
	"consense_terminal_type" => {
		"perl" => '"T\\n"',
	},
	"consense_outfile" => {
	},
	"consense_treefile" => {
	},
	"output" => {
	},
	"print_tree" => {
		"perl" => '($value)? "" : "3\\n"',
	},
	"print_treefile" => {
		"perl" => '($value)? "" : "4\\n"',
	},
	"indent_tree" => {
		"perl" => ' " && indenttree -o outtree.indent outtree" ',
	},
	"printdata" => {
		"perl" => '($value)? "1\\n" : ""',
	},
	"other_options" => {
	},
	"outgroup" => {
		"perl" => '(defined $value && $value != $vdef)? "O\\n$value\\n" : ""',
	},
	"triangular" => {
	},
	"outfile" => {
	},
	"treefile" => {
	},
	"indented_treefile" => {
	},
	"params" => {
	},
	"confirm" => {
		"perl" => '"Y\\n"',
	},
	"terminal_type" => {
		"perl" => '"0\\n"',
	},
	"tmp_params" => {
	},

    };

    $self->{FILENAMES}  = {
	"consense_outfile" => 'outfile.consense',
	"consense_treefile" => 'outtree.consense',
	"outfile" => 'outfile',
	"treefile" => 'outtree',
	"indented_treefile" => 'outtree.indent',
	"params" => 'params',
	"tmp_params" => '*.params',

    };

    $self->{SEQFMT}  = {

    };

    $self->{GROUP}  = {
	"neighbor" => 0,
	"distance_method" => 1,
	"infile" => -10,
	"jumble" => 20,
	"jumble_seed" => 19,
	"multiple_dataset" => 10,
	"datasets_nb" => 9,
	"consense" => 10,
	"consense_confirm" => 1000,
	"consense_terminal_type" => -2,
	"print_tree" => 1,
	"print_treefile" => 1,
	"indent_tree" => 1000,
	"printdata" => 1,
	"outgroup" => 1,
	"triangular" => 1,
	"confirm" => 1000,
	"terminal_type" => -1,

    };

    $self->{BY_GROUP_PARAMETERS}  = [
	"infile",
	"consense_terminal_type",
	"terminal_type",
	"neighbor",
	"other_options",
	"jumble_opt",
	"outfile",
	"treefile",
	"bootstrap",
	"indented_treefile",
	"params",
	"multiple_seed",
	"tmp_params",
	"consense_outfile",
	"consense_treefile",
	"output",
	"distance_method",
	"triangular",
	"printdata",
	"print_tree",
	"outgroup",
	"print_treefile",
	"datasets_nb",
	"multiple_dataset",
	"consense",
	"jumble_seed",
	"jumble",
	"confirm",
	"consense_confirm",
	"indent_tree",

    ];

    $self->{SIZE}  = {

    };

    $self->{ISHIDDEN}  = {
	"neighbor" => 1,
	"distance_method" => 0,
	"infile" => 0,
	"jumble_opt" => 0,
	"jumble" => 0,
	"jumble_seed" => 0,
	"bootstrap" => 0,
	"multiple_dataset" => 0,
	"datasets_nb" => 0,
	"multiple_seed" => 0,
	"consense" => 0,
	"consense_confirm" => 1,
	"consense_terminal_type" => 1,
	"consense_outfile" => 0,
	"consense_treefile" => 0,
	"output" => 0,
	"print_tree" => 0,
	"print_treefile" => 0,
	"indent_tree" => 0,
	"printdata" => 0,
	"other_options" => 0,
	"outgroup" => 0,
	"triangular" => 0,
	"outfile" => 0,
	"treefile" => 0,
	"indented_treefile" => 0,
	"params" => 0,
	"confirm" => 1,
	"terminal_type" => 1,
	"tmp_params" => 0,

    };

    $self->{ISCOMMAND}  = {
	"neighbor" => 1,
	"distance_method" => 0,
	"infile" => 0,
	"jumble_opt" => 0,
	"jumble" => 0,
	"jumble_seed" => 0,
	"bootstrap" => 0,
	"multiple_dataset" => 0,
	"datasets_nb" => 0,
	"multiple_seed" => 0,
	"consense" => 0,
	"consense_confirm" => 0,
	"consense_terminal_type" => 0,
	"consense_outfile" => 0,
	"consense_treefile" => 0,
	"output" => 0,
	"print_tree" => 0,
	"print_treefile" => 0,
	"indent_tree" => 0,
	"printdata" => 0,
	"other_options" => 0,
	"outgroup" => 0,
	"triangular" => 0,
	"outfile" => 0,
	"treefile" => 0,
	"indented_treefile" => 0,
	"params" => 0,
	"confirm" => 0,
	"terminal_type" => 0,
	"tmp_params" => 0,

    };

    $self->{ISMANDATORY}  = {
	"neighbor" => 0,
	"distance_method" => 1,
	"infile" => 1,
	"jumble_opt" => 0,
	"jumble" => 0,
	"jumble_seed" => 1,
	"bootstrap" => 0,
	"multiple_dataset" => 0,
	"datasets_nb" => 1,
	"multiple_seed" => 1,
	"consense" => 0,
	"consense_confirm" => 0,
	"consense_terminal_type" => 0,
	"consense_outfile" => 0,
	"consense_treefile" => 0,
	"output" => 0,
	"print_tree" => 0,
	"print_treefile" => 0,
	"indent_tree" => 0,
	"printdata" => 0,
	"other_options" => 0,
	"outgroup" => 0,
	"triangular" => 0,
	"outfile" => 0,
	"treefile" => 0,
	"indented_treefile" => 0,
	"params" => 0,
	"confirm" => 0,
	"terminal_type" => 0,
	"tmp_params" => 0,

    };

    $self->{PROMPT}  = {
	"neighbor" => "",
	"distance_method" => "Distance method",
	"infile" => "Distances matrix File",
	"jumble_opt" => "Randomize options",
	"jumble" => "Randomize (jumble) input order (J)",
	"jumble_seed" => "Random number seed for jumble (must be odd)",
	"bootstrap" => "Bootstrap options",
	"multiple_dataset" => "Analyze multiple data sets (M)",
	"datasets_nb" => "How many data sets",
	"multiple_seed" => "Random number seed for multiple dataset (must be odd)",
	"consense" => "Compute a consensus tree",
	"consense_confirm" => "",
	"consense_terminal_type" => "",
	"consense_outfile" => "",
	"consense_treefile" => "",
	"output" => "Output options",
	"print_tree" => "Print out tree (3)",
	"print_treefile" => "Write out trees onto tree file (4)",
	"indent_tree" => "Indent treefile",
	"printdata" => "Print out the data at start of run (1)",
	"other_options" => "Other options",
	"outgroup" => "Outgroup species (default, use as outgroup species 1) (O)",
	"triangular" => "Matrix format",
	"outfile" => "",
	"treefile" => "",
	"indented_treefile" => "",
	"params" => "",
	"confirm" => "",
	"terminal_type" => "",
	"tmp_params" => "",

    };

    $self->{ISSTANDOUT}  = {
	"neighbor" => 0,
	"distance_method" => 0,
	"infile" => 0,
	"jumble_opt" => 0,
	"jumble" => 0,
	"jumble_seed" => 0,
	"bootstrap" => 0,
	"multiple_dataset" => 0,
	"datasets_nb" => 0,
	"multiple_seed" => 0,
	"consense" => 0,
	"consense_confirm" => 0,
	"consense_terminal_type" => 0,
	"consense_outfile" => 0,
	"consense_treefile" => 0,
	"output" => 0,
	"print_tree" => 0,
	"print_treefile" => 0,
	"indent_tree" => 0,
	"printdata" => 0,
	"other_options" => 0,
	"outgroup" => 0,
	"triangular" => 0,
	"outfile" => 0,
	"treefile" => 0,
	"indented_treefile" => 0,
	"params" => 0,
	"confirm" => 0,
	"terminal_type" => 0,
	"tmp_params" => 0,

    };

    $self->{VLIST}  = {

	"distance_method" => ['neighbor','Neighbor-joining','upgma','UPGMA',],
	"jumble_opt" => ['jumble','jumble_seed',],
	"bootstrap" => ['multiple_dataset','datasets_nb','multiple_seed','consense',],
	"output" => ['print_tree','print_treefile','indent_tree','printdata',],
	"other_options" => ['outgroup','triangular',],
	"triangular" => ['square','Square','lower','Lower-triangular','upper','Upper-triangular',],
    };

    $self->{FLIST}  = {

	"triangular" => {
		'lower' => '"L\\n"',
		'square' => '""',
		'upper' => '"R\\n"',

	},
    };

    $self->{SEPARATOR}  = {

    };

    $self->{VDEF}  = {
	"distance_method" => 'neighbor',
	"jumble" => '0',
	"multiple_dataset" => '0',
	"consense" => '0',
	"print_tree" => '1',
	"print_treefile" => '1',
	"indent_tree" => '1',
	"printdata" => '0',
	"outgroup" => '1',
	"triangular" => 'square',

    };

    $self->{PRECOND}  = {
	"neighbor" => { "perl" => '1' },
	"distance_method" => { "perl" => '1' },
	"infile" => { "perl" => '1' },
	"jumble_opt" => { "perl" => '1' },
	"jumble" => {
		"perl" => 'not $multiple_dataset',
	},
	"jumble_seed" => {
		"perl" => '$jumble',
	},
	"bootstrap" => { "perl" => '1' },
	"multiple_dataset" => { "perl" => '1' },
	"datasets_nb" => {
		"perl" => '$multiple_dataset',
	},
	"multiple_seed" => {
		"perl" => '$multiple_dataset',
	},
	"consense" => {
		"perl" => '$multiple_dataset && $print_treefile',
	},
	"consense_confirm" => {
		"perl" => '$consense',
	},
	"consense_terminal_type" => {
		"perl" => '$consense',
	},
	"consense_outfile" => {
		"perl" => '$consense',
	},
	"consense_treefile" => {
		"perl" => '$consense',
	},
	"output" => { "perl" => '1' },
	"print_tree" => { "perl" => '1' },
	"print_treefile" => { "perl" => '1' },
	"indent_tree" => { "perl" => '1' },
	"printdata" => { "perl" => '1' },
	"other_options" => { "perl" => '1' },
	"outgroup" => {
		"perl" => '$distance_method eq "neighbor"',
	},
	"triangular" => { "perl" => '1' },
	"outfile" => { "perl" => '1' },
	"treefile" => {
		"perl" => '$print_treefile',
	},
	"indented_treefile" => {
		"perl" => '$print_treefile && $indent_tree',
	},
	"params" => { "perl" => '1' },
	"confirm" => { "perl" => '1' },
	"terminal_type" => { "perl" => '1' },
	"tmp_params" => { "perl" => '1' },

    };

    $self->{CTRL}  = {
	"jumble_seed" => {
		"perl" => {
			'$value <= 0 || (($value % 2) == 0)' => "Random number seed must be odd",
		},
	},
	"datasets_nb" => {
		"perl" => {
			'$value > 1000' => "there must be no more than 1000 datasets for this server",
		},
	},
	"multiple_seed" => {
		"perl" => {
			'$value <= 0 || (($value % 2) == 0)' => "Random number seed must be odd",
		},
	},
	"outgroup" => {
		"perl" => {
			'defined $value && $value < 1' => "Please enter a value greater than 0",
		},
	},

    };

    $self->{PIPEOUT}  = {
	"consense_treefile" => {
		 '1' => "phylip_tree",
	},
	"treefile" => {
		 '1' => "phylip_tree",
	},

    };

    $self->{WITHPIPEOUT}  = {

    };

    $self->{PIPEIN}  = {
	"infile" => {
		 "phylip_dist" => '1',
	},

    };

    $self->{WITHPIPEIN}  = {

    };

    $self->{ISCLEAN}  = {
	"neighbor" => 0,
	"distance_method" => 0,
	"infile" => 0,
	"jumble_opt" => 0,
	"jumble" => 0,
	"jumble_seed" => 0,
	"bootstrap" => 0,
	"multiple_dataset" => 0,
	"datasets_nb" => 0,
	"multiple_seed" => 0,
	"consense" => 0,
	"consense_confirm" => 0,
	"consense_terminal_type" => 0,
	"consense_outfile" => 0,
	"consense_treefile" => 0,
	"output" => 0,
	"print_tree" => 0,
	"print_treefile" => 0,
	"indent_tree" => 0,
	"printdata" => 0,
	"other_options" => 0,
	"outgroup" => 0,
	"triangular" => 0,
	"outfile" => 0,
	"treefile" => 0,
	"indented_treefile" => 0,
	"params" => 0,
	"confirm" => 0,
	"terminal_type" => 0,
	"tmp_params" => 0,

    };

    $self->{ISSIMPLE}  = {
	"neighbor" => 0,
	"distance_method" => 0,
	"infile" => 1,
	"jumble_opt" => 0,
	"jumble" => 0,
	"jumble_seed" => 0,
	"bootstrap" => 0,
	"multiple_dataset" => 0,
	"datasets_nb" => 0,
	"multiple_seed" => 0,
	"consense" => 0,
	"consense_confirm" => 0,
	"consense_terminal_type" => 0,
	"consense_outfile" => 0,
	"consense_treefile" => 0,
	"output" => 0,
	"print_tree" => 0,
	"print_treefile" => 0,
	"indent_tree" => 0,
	"printdata" => 0,
	"other_options" => 0,
	"outgroup" => 0,
	"triangular" => 0,
	"outfile" => 0,
	"treefile" => 0,
	"indented_treefile" => 0,
	"params" => 0,
	"confirm" => 0,
	"terminal_type" => 0,
	"tmp_params" => 0,

    };

    $self->{PARAMFILE}  = {
	"distance_method" => "params",
	"jumble" => "params",
	"multiple_dataset" => "params",
	"multiple_seed" => "params",
	"consense_confirm" => "consense.params",
	"consense_terminal_type" => "consense.params",
	"print_tree" => "params",
	"print_treefile" => "params",
	"printdata" => "params",
	"outgroup" => "params",
	"triangular" => "params",
	"confirm" => "params",
	"terminal_type" => "params",

    };

    $self->{COMMENT}  = {
	"print_tree" => [
		"Tells the program to print a semi-graphical picture of the tree in the outfile.",
	],
	"print_treefile" => [
		"Tells the program to save the tree in a treefile (a standard representation of trees where the tree is specified by a nested pairs of parentheses, enclosing names and separated by commas).",
	],

    };

    $self->{SCALEMIN}  = {

    };

    $self->{SCALEMAX}  = {

    };

    $self->{SCALEINC}  = {

    };

    $self->{INFO}  = {

    };

# -- end of definitions extracted from /local/gensoft/lib/Pise/5.a/PerlDef/neighbor.pm



    $self->_init_params(@params);

    return $self;
}



1; # Needed to keep compiler happy

