# ChangeLog

Path: | ChangeLog
Last Update: | Thu Nov 19 15:47:02 +0000 2009

2009-09-02 Naohisa Goto <ng@bioruby.org>

            * BioRuby 1.3.1 is released.

2009-09-02 Naohisa Goto <ng@bioruby.org>

            * lib/bio/version.rb

              Preparation for bioruby-1.3.1 release.
              (commit 3d86bc6d519c4c3319e5a1b2ca36f8f5177f127f)

2009-08-31 Naohisa Goto <ng@bioruby.org>

            * lib/bio/sequence/compat.rb

              Document bug fix: Bio::Sequence::(NA|AA|Generic)#to_fasta are
              currently not deprecated.
              (commit 0e0f888a73a60c0f0a7b103019aeb82c8f063c4e)

2009-08-28 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/sim4/report.rb

              Bug fix: parse error when unaligned regions exist. Thanks to
              Tomoaki NISHIYAMA who reports the bug ([BioRuby] SIM4 parser).

            * test/unit/bio/appl/sim4/test_report.rb,
              test/data/sim4/complement-A4.sim4

              To confirm the bug fix, tests are added with new test data.
              (commit 02d531e36ecf789f232cf3e05f85391b60279f00)

2009-08-27 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/sim4/report.rb

              Bug fix: parse errpr when the alignment of an intron is splitted
              into two lines. Thanks to Tomoaki NISHIYAMA who sent the patch
              ([BioRuby] SIM4 parser).
              (commit 137ec4c3099236c89ac4a0157d0c77ba13d1875c)

2009-08-27 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/sim4/report.rb

              Ruby 1.9 support: String#each_line instead of String#each
              (commit b65f176f3be74c21a8bb8fc2a6f204fb8ab08fd6)

2009-08-27 Naohisa Goto <ng@bioruby.org>

            * test/unit/bio/appl/sim4/test_report.rb,
              test/data/sim4/simple-A4.sim4, test/data/sim4/simple2-A4.sim4

              Newly added unit tests for Bio::Sim4::Report with test data.
              The test data is based on the data provided by Tomoaki NISHIYAMA
              ([BioRuby] SIM4 parser), and most of the sequence data is
              replaced by random sequence.
              (commit 0f53916dd728b871f02d1caf0c5105a2e1c58bc4)

2009-08-18 Naohisa Goto <ng@bioruby.org>

            * COPYING, COPYING.ja, GPL, LGPL, LEGAL

              License files are added. COPYING, COPYING.ja, GPL, LGPL are taken
              from Ruby's svn repository.  LEGAL is written for BioRuby.
              (commit c65531331e840562ac7342f1896f7e2a3aac6c88)

            * README.rdoc

              Added descriptions about license to refer COPYING and LEGAL.
              (commit d88015a2e3b2c5f7c2a931261819b908084d0179)

            * COPYING

              Modified COPYING for BioRuby, following Matz's recommendation
              in [ruby-list:46293].
              (commit 2c30e7342e33c878bd7132a302974364c54caad9)

2009-05-06 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/fasta.rb, lib/bio/appl/fasta/format10.rb

              Restored Bio::Fasta.parser for keeping compatibility, and added
              forgotten require.
              (commit 97b9284109c9a4431b92eab208509e1df6069b4b)

2009-05-02 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/fasta.rb

              * Bug fix: Bio::Fasta::Report should be autoloaded.
              * Removed useless method Bio::Fasta::Report.parser because
                only the "format10" parser is available for a long time
                and dynamic require is a potential security hole.
              * Removed "require" lines in Bio::Fasta#parse_result.
              (commit 3d3edc44127f4fd97abcc17a859e36623facdc7c)

2009-05-02 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/fasta/format10.rb

              Bug Fix: stack overflow problem, and added support for multiple
              query sequences.

              * Bug fix: stack overflow problem. Thanks to Fredrik Johansson who
                reports the bug ([BioRuby] Made a change in format10.rb).
              * Changed to set @entry_overrun when a report containing multiple
                query sequences' results is given.
              * New methods Bio::Fasta::Report#query_def and query_len.
              * To support reading a search result with multiple query sequences
                by using Bio::FlatFile, a flatfile splitter class
                Bio::Fasta::Report::FastaFormat10Splitter is newly added.
              (commit e57349594427ad1a51979c9d4e0c3efcffd160c2)

2009-04-27 Naohisa Goto <ng@bioruby.org>

            * test/unit/bio/test_feature.rb, test/unit/bio/test_reference.rb

              class name conflict of NullStderr
              (commit 1607b60d905eb8cb5ca289e357cbb2cbb7a118ff)

            * test/unit/bio/appl/test_blast.rb

              Bug fix: method redefined: TestBlast#test_self_local
              (commit 9caa4c9d94126b3568c439878876062c84afbdec)

            * test/unit/bio/appl/hmmer/test_report.rb
              Bug fix: method name conflict:
              TestHMMERReportClassMethods#test_reports_ary
              (commit cc3e1b85cf885736a7b1293c7e0951e099cd7e6b)

            * test/unit/bio/appl/bl2seq/test_report.rb

              * Bug fix: method redefined: TestBl2seqReport#test_undefed_methods.
                To fix the bug, the second "test_undefed_methods" is renamed to
                "test_undefed_methods_for_iteration".
              * Assertions are changed in the first "test_undefed_methods".
              * Fixed typo.
              (commit 7e1a550de3dffde3fd8808803e44f35072e4d40b)

2009-04-27 Naohisa Goto <ng@bioruby.org>

            * lib/bio/util/restriction_enzyme/range/sequence_range/calculated_cuts.rb
              Bug fix: attribute "strands_for_display" is disabled because the
              method definition with the same name overwrites the attribute
              definition.
              (commit af07e2784faacc51366ddfab5bedd45841734f53)

            * lib/bio/db/embl/embl.rb

              Bug fix: removed duplicated alias
              (commit 65c360f39580322b5eee64b7c2d8274ff7b8dfff)

            * lib/bio/appl/pts1.rb

              Bug fix: removed unused attribute "function" in Bio::PTS1
              because method definition with the same name appeared later
              wipes out the attribute definition.
              (commit 81cbe9da55217d186e6dc9c1bfb56a39fba73590)

2009-04-27 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/blast/format0.rb

              Bug fix: forgotten "if false #dummy" in the attribute "query_to".
              (commit 7c2e8d0d11baf8cb9e25207ba5b27d4e9d756054)

            * lib/bio/appl/blast.rb

              Bug fix: suppressing warning messages when $VERBOSE=true.

              * To suppress warining message "lib/bio/appl/blast.rb:402: warning:
                useless use of :: in void context", a dummy variable is added.
              * The attribute "server" is changed to attr_reader because "server="
                is defined later.
              (commit f9404276d2ddcf15966cab74c419733ccd748af2)

2009-04-27 Naohisa Goto <ng@bioruby.org>

            * test/unit/bio/test_sequence.rb

              Fixed test name overwriting another test name in TestSequence.
              Fixed by Andrew Grimm at git://github.com/agrimm/bioruby.git
              in Thu Feb 19 22:30:26 2009 +1100.
              (commit a6c39a719b284a43fe8c67edc1f2826d2941647f)

2009-04-26 Naohisa Goto <ng@bioruby.org>

            * test/unit/bio/appl/gcg/test_msf.rb,
              test/data/gcg/pileup-aa.msf

              Newly added unit tests for Bio::GCG::Msf with test data
              (commit a1819cd3b772300ef5bea2ebb63376e5b9fc64da)

2009-04-23 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/gcg/msf.rb

              * Bug fix: incorrect parsing of GCG clustalw+ results.
              * Small refactoring of codes
              (commit 2eae8f722aa888c85d54aa958eb117d49ce42f8b)

2009-04-21 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/gcg/msf.rb

              * Bug fix: Bio::GCG::Msf fails parsing when two dots are appeared
                at the end of a line. Thanks to Fredrik Johansson who reports the
                bug and send the patch ([BioRuby] Parsing MSF alignment file).
              * bug fix: misspelling of "ALIGNMENT".
              (commit 44ca52443e0249f54c43f92d08cf083cdd12c692)

2009-04-21 Naohisa Goto <ng@bioruby.org>

            * lib/bio/io/pubmed.rb

              Bug fix: Bio::PubMed#efetch should return an array of string
              objects. Thanks to Masahide Kikkawa and Fredrik Johansson
              who report the bug (in "[BioRuby] Bio::PubMed.efetch, bug?"
              and "[BioRuby] PubMed.efetch error").
              (commit a48a9a35b87dead069fe328ba7086977304af995)

            * test/functional/bio/io/test_pubmed.rb

              Newly added functional test for Bio::PubMed.
              (commit bf5ba6d4503f3ddb0ca31673882f5b396a932bbe)

2009-04-21 Naohisa Goto <ng@bioruby.org>

            * lib/bio/io/ncbirest.rb

              * Bug fix: Bio::NCBI::REST#esearch ignores hash["retstart"].
              * In Bio::NCBI::REST#esearch, the priority of limit and
                hash["retmax"] is clarified: limit is used unless it is nil.
                In addition, default value of limit is changed to nil. If both
                limit and hash["retmax"] are nil, default value 100 is used.
              * Bio::NCBI::REST::NCBI_INTERVAL is changed to 1.
              (commit fc0339fe8a42cd00199cfdc938590ae9626551bc)

2009-03-19 Naohisa Goto <ng@bioruby.org>

            * lib/bio/io/ncbirest.rb

              Bug fix: Bio::PubMed.efetch/esearch ignores retmax after refactoring
              of Bio::PubMed.  efetch/esearch methods in Bio::NCBI::REST are also
              affected.  Thanks to Craig Knox who reports the bug ([BioRuby]
              efetch/esearch broken).  Bug fix by Toshiaki Katayama.
              (commit 51c3223e033b2992a7bd95da282f88164406ff92)

2009-03-19 Naohisa Goto <ng@bioruby.org>

            * doc/Tutorial.rd

              GO example using Ensembl API is moved to Appendix.
              (commit d677c3d7cbd2f4ff6193255e0e30366ecd0aa421)

              fixed RD text formatting issues
              (commit 642577ae70647f8bd0ae3bcc8ddc118cecc886c7)

            * doc/Tutorial.rd.html

              doc/Tutorial.rd.html is regenerated
              (commit dd878d3ecd83ad5e61a21bbf90d27d1c89d5f12d)

2009-03-18 Naohisa Goto <ng@bioruby.org>

            * doc/Tutorial.rd

              Reverted a Blast example code because it aims to tell usage of
              blocks to explore a Blast report, and getting the "result" is
              only a side effect and not the main purpose.
              (commit db172eb1e5f1cbc17317bff8043cc07bf6597073)

2009-03-18 Pjotr Prins <pjotr.public01@thebird.nl>

            * doc/Tutorial.rd

              Updated Tutorial.
              (commit b3363ee94cfb86540a7d286ccac608b74737b30d)

              Updated tutorial with links and gene ontology example
              by Marc Hoeppner.
              (commit 27a5019ca7a41211055550f9731672aa71a3a4b3)

              Fixed doctests in documentation.
              (commit 9a21a1750a9584152fae669be132af89086e7d5f)

              Added working BLAST example.
              (commit 45c27f109f069db3b6208fd59cc2b683a5bca5a9)

              Added BLAST example. All doctests work again in Tutorial.rd.
              (commit 05edf3092d0322b8f2775e60448700024d8cb343)

              Slightly improved remarks. Tutorial.rd runs its doctests.
              (commit 541a4cf0d9d0d3904f1570e1258a847a22f9238b)

              reference to github.com/pjotrp/bioruby-support
              (commit ec5dfb1544e32034457b0dd36a9dc50fef6c0fbe)

              Added info on how to split large BLAST XML files.
              (commit 6c9a80cde4be6c4c3d02b77c44dfa8bfbf0a41ff)

              Updated Tutorial
              (commit 07267e2d9c5b774bb0f41b795f6be1f24ff175ba)

2009-03-17 Raoul Jean Pierre Bonnal <ilpuccio.febo@gmail.com>

            * lib/bio/db/biosql/sequence.rb

              Fixed: taxonomy, do not report node_rank of type "class".
              GenBanks Tests I/O passed.
              (commit ba5400eaf6de0f38341825cb0fbc24ca1d99eeba)

2009-03-17 Raoul Jean Pierre Bonnal <ilpuccio.febo@gmail.com>

            * test/unit/bio/db/biosql/tc_biosql.rb

              Removed last "\n" from reference GenBank string
              (commit 2de87ceef220056a502c5a9a3457abdf1d93fab0)

2009-03-17 Raoul Jean Pierre Bonnal <ilpuccio.febo@gmail.com>

            * lib/bio/db/biosql/sequence.rb

              Fix: reference deletion from bioentry deletion, when reference
              is a leaf (no more bioentries connected to it)
              (commit 6f3195a023cab8ee64eb3e3bb9c491534cd80603)

2009-03-17 Raoul Jean Pierre Bonnal <ilpuccio.febo@gmail.com>

            * lib/bio/io/biosql/ar-biosql.rb

              Added: relation between bioentry and refernces, also through
              references by bioentry_reference. This is useful to accomplish
              complete bioentry's delete.
              (commit d9e5876231d451c9ab1a2e75702f9fe70b1509b8)

2009-03-17 Raoul Jean Pierre Bonnal <ilpuccio.febo@gmail.com>

            * test/unit/bio/db/biosql/tc_biosql.rb

              Fixed: title test
              (commit 45e2d5e21bc1f93240827dee2e46ac02d24cf696)

2009-03-17 Raoul Jean Pierre Bonnal <ilpuccio.febo@gmail.com>

            * lib/bio/db/genbank/common.rb

              Fix: Delete added dot at the end of TITLE.
              (commit 2a29c9e7fd41da9d6bf065b3d6dbd473e4d03bbe)

2009-03-17 Raoul Jean Pierre Bonnal <ilpuccio.febo@gmail.com>

            * lib/bio/db/biosql/sequence.rb

              Add: bioentry_qualifier_value recognize if it's handling data
              (reader) and format it accordingly with GenBank/EMBL format
              ex: 26-SEP-2006 .
              (commit 05ba3f1647d4cc71747ada95c9bb7f2a5a44b518)

2009-03-17 Raoul Jean Pierre Bonnal <ilpuccio.febo@gmail.com>

            * lib/bio/db/biosql/biosql_to_biosequence.rb

              Fixed: date_modified, the code is moved to
              Bio::SQL::Sequence#bioentry_qualifier_anchor#method_reader.
              It's most an exercise of style than good programming.
              date_modifier reader should be a method apart.
              (commit c9a980877c9222e05aa0d9163ba51aa2c77a7146)

2009-03-17 Raoul Jean Pierre Bonnal <ilpuccio.febo@gmail.com>

            * test/unit/bio/db/biosql/tc_biosql.rb,
              test/unit/bio/db/biosql/test_biosql.rb,
              test/unit/bio/db/biosql/ts_suite_biosql.rb

              Add: BioSQL's TestSuite, alpha stage
              (commit be1839b3bf3008fe234e8f89d85302caef83398f)

2009-03-17 Raoul Jean Pierre Bonnal <ilpuccio.febo@gmail.com>

            * lib/bio/db/biosql/biosql_to_biosequence.rb

              Fix: date_modifier biosequence adapter
              (commit a7c1c717e1684fd9117fc2d096e8d6e7c647b62d)

2009-03-17 Raoul Jean Pierre Bonnal <ilpuccio.febo@gmail.com>

            * test/unit/bio/db/biosql/test_biosql.rb

              Added preliminar tests using connection with jdbcmysql.
              Test are focused on input/output coherence.
              (commit 0ada9f8b4bb8553bf076caca76bc76a4d6791c6b)

2009-03-17 Raoul Jean Pierre Bonnal <ilpuccio.febo@gmail.com>

            * lib/bio/db/biosql/biosql_to_biosequence.rb

              Fixed: GI:xxxx reference on VERSION's line using
              biosql/to_biosequence.output(:genbank)
              (commit 35e1dce1a75ed967ec707457ed3655ce927f83c3)

2009-03-17 Raoul Jean Pierre Bonnal <ilpuccio.febo@gmail.com>

            * lib/bio/db/biosql/sequence.rb

              added other_seqids as alias of identifier, for the adapter.
              Export problem of GI in output(:genbank) from biosql/biosequence.
              (commit 7f69ea73dcd28e76743bd5213c3719cf7d9d44a0)

2009-03-17 Raoul Jean Pierre Bonnal <ilpuccio.febo@gmail.com>

            * lib/bio/db/biosql/biosql_to_biosequence.rb

              (Changed comments only) Added TODOs as comments:
              to_biosequence.output(:genbank) some major and minor problems.
                1) Major. GI: is not exported IN(VERSION     X64011.1  GI:44010),
                   OUT(VERSION     X64011.1)
                1.1) Db storage is ok, GI is saved into identifier of bioentry
                2) Moderate. date wrong format IN(26-SEP-2006), OUT(2006-09-26)
                3) Minor. Organism in output as more terms.
                4) Minor. Title has a dot at the end, input was without

              ref for GI in genbank are functions ncbi_gi_number/other_seqids
              (commit 03662955a45e1c3d5d32150b423a92d40c0c33c7)

2009-03-17 Raoul Jean Pierre Bonnal <ilpuccio.febo@gmail.com>

            * lib/bio/io/sql.rb

              get and first converted from DataMapper to ActiveRecord
              (commit 78b37c61bbb0a16bbee6c3dd16bff7c292e77695)

2009-03-17 Raoul Jean Pierre Bonnal <ilpuccio.febo@gmail.com>

            * lib/bio/db/biosql/sequence.rb

              converted syntax of first function from DataMapper to ActiveRecord
              (commit 822a35794b958906e5d4bfb6d5b9d74efb360ea7)

              converted .get! method in find with conditions
              (commit 1f3012ba93a9c462e8b1daa762372a55534db29c)

2009-03-17 Raoul Jean Pierre Bonnal <ilpuccio.febo@gmail.com>

            * lib/bio/io/biosql/biosql.rb

              establish_connection rewrite and update Class.first call with
              ActiveRecord syntax. Coming from DataMapper.
              (commit 66fb6ff597a2ebf2f2dc1ebe7e505fbcc46c993c)

2009-03-17 Raoul Jean Pierre Bonnal <ilpuccio.febo@gmail.com>

            * lib/bio/db/biosql/sequence.rb

              Version developed with DataMapper, need to be tested with
              ActiveRecord -current ORM-.
              (commit 7bf5d24364fce8f3a466697e479af5f28c672265)

2009-03-17 Raoul Jean Pierre Bonnal <ilpuccio.febo@gmail.com>

            * lib/bio/io/biosql/config/database.yml

              Configured development database with jdbcmysql adapter.
              (commit 7e143b1d0451bce6865e560febc5c57048210416)

2009-03-17 Raoul Jean Pierre Bonnal <ilpuccio.febo@gmail.com>

            * lib/bio/io/biosql/ar-biosql.rb

              Newly added lib/bio/io/biosql/ar-biosql.rb: In one file
              definition of all  BioSQL's ActiveRecords classes.
              (commit 87f7bc6ac844583adc07e409c9fac7fa1f275d2b)

              class Bioentry: added has_many obejct_bioentry_path and
              subject_bioentry_path.
              (commit e969eae59d0de098e094ea21007c34371bab3bdd)

              class BioentryRelationship: added relation to Term class.
              (commit f77b28045f0631391c6f4ad4e9eed15d296bec95)

              class Biosequence: changed to composite primary keys,
              :bioentry_id, :version.
              (commit c6683346e4c13d8969bb859e882698b90d0828f1)

              class SeqfeatureQualifierValue: find function deleted, wrong here.
              (commit 89f64af363d0b204e50ea71924909724d56bccc4)

            * lib/bio/io/sql.rb

              Separated connection (see lib/bio/io/biosql.rb) from definition
              of public methods.
              (commit 24b9e6473ce36e3151c560ea26c3b95105656ef4)

2009-03-17 Raoul Jean Pierre Bonnal <ilpuccio.febo@gmail.com>

            * lib/bio/io/biosql

              To integrate BioSQL ActiveRecords classes to one file, as the
              first step, following 28 files listed below are deleted. In the
              later        commit, they will be integrated into one file,
              lib/bio/io/biosql/ar-biosql.rb.
              (commit 0ea9f08b36e10e50c855d4346194849e8e7a263b)

                 * lib/bio/io/biosql/biodatabase.rb
                 * lib/bio/io/biosql/bioentry.rb
                 * lib/bio/io/biosql/bioentry_dbxref.rb
                 * lib/bio/io/biosql/bioentry_path.rb
                 * lib/bio/io/biosql/bioentry_qualifier_value.rb
                 * lib/bio/io/biosql/bioentry_reference.rb
                 * lib/bio/io/biosql/bioentry_relationship.rb
                 * lib/bio/io/biosql/biosequence.rb
                 * lib/bio/io/biosql/comment.rb
                 * lib/bio/io/biosql/dbxref.rb
                 * lib/bio/io/biosql/dbxref_qualifier_value.rb
                 * lib/bio/io/biosql/location.rb
                 * lib/bio/io/biosql/location_qualifier_value.rb
                 * lib/bio/io/biosql/ontology.rb
                 * lib/bio/io/biosql/reference.rb
                 * lib/bio/io/biosql/seqfeature.rb
                 * lib/bio/io/biosql/seqfeature_dbxref.rb
                 * lib/bio/io/biosql/seqfeature_path.rb
                 * lib/bio/io/biosql/seqfeature_qualifier_value.rb
                 * lib/bio/io/biosql/seqfeature_relationship.rb
                 * lib/bio/io/biosql/taxon.rb
                 * lib/bio/io/biosql/taxon_name.rb
                 * lib/bio/io/biosql/term.rb
                 * lib/bio/io/biosql/term_dbxref.rb
                 * lib/bio/io/biosql/term_path.rb
                 * lib/bio/io/biosql/term_relationship.rb
                 * lib/bio/io/biosql/term_relationship_term.rb
                 * lib/bio/io/biosql/term_synonym.rb

2009-03-17 Naohisa Goto <ng@bioruby.org>

            * Rakefile

              Rake::Task#execute now needs to take an argument. Currently,
              nil is given.

2009-02-20 Naohisa Goto <ng@bioruby.org>

            * BioRuby 1.3.0 is released.

2009-02-19 Naohisa Goto <ng@bioruby.org>

            * lib/bio/version.rb

              Preparation for bioruby-1.3.0 release.
              (commit fd7fc9f78bc5f4d9a10b3c0d457d9781c9ec2e49)

            * bioruby.gemspec.erb

              Fixed a logic to determine whether in git repository, and file
              lists are changed to be sorted.
              (commit ede0c0d7aeab078b6183c4e0e7c74faec32739f7)

2009-02-18 Naohisa Goto <ng@bioruby.org>

            * README.rdoc

              Added list of document files bundled in the BioRuby distribution.
              (commit 92748f848e4708766e44c22b2f02ac662491971f)

2009-02-10 Naohisa Goto <ng@bioruby.org>

            * KNOWN_ISSUES.rdoc

              Added details about the text mode issue on mswin32/mingw32/bccwin32
              and about non-UNIX/Windows systems.
              (commit 342a167a23d3b078bd77b3f16f0ceb1aa071df66)

2009-02-09 Naohisa Goto <ng@bioruby.org>

            * test/unit/bio/db/test_gff.rb

              Test bug fix: test_gff.rb failed in some environment (e.g. Windows)
              because the default formatting rule of Float#to_s depends on the
              libc implementation.
              (commit f39bf88ed6a41bd328372ee7de7a23902235f833)

2009-02-06 Naohisa Goto <ng@bioruby.org>

            * lib/bio/db/gff.rb, test/unit/bio/db/test_gff.rb

              * Bug fix: Bio::GFF::GFF3::Record#id and #id= should be changed
                to follow the previous incompatible change of @attributes.
                Thanks to Tomoaki NISHIYAMA who reports the bug ([BioRuby]
                GFF3 status (possible bug?)).
              * Unit tests are added.
              (commit 5258d88ef98a12fd7829eb86aa8664a18a672a43)
              (commit c0c7708b3e91b0d2f2d0d50a4a0ba36928057cc8)

2009-02-05 Naohisa Goto <ng@bioruby.org>

            * Rakefile

              New task "tutorial2html" to generate html from doc/Tutorial.rd
              and doc/Tutorial.rd.ja.
              (commit 8d66fae59477f01f12b2fa3509ea34c371102725)

            * doc/Tutorial.rd.html, doc/Tutorial.rd.ja.html

              Automatically generated tutorial html from RD formatted documents.
              (commit 90c4a23eea08b06dd758aaa0a53bea789602d252)

            * doc/bioruby.css

              Newly added stylesheet for the tutorial html files. The bioruby.css
              have been used in http://bioruby.org/ and have been maintained by
              Toshiaki Katayama.
              (commit b69dc243787525de065bdf2e6b7da68d6079ab91)

            * test/runner.rb

              Added workaroud for test-unit-2.0.x.
              (commit 475ac6a6b38e8df30de3d9bf4c7e810759ab023d)

2009-02-04 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/blast/format0.rb

              Bug fix: a null line can be inserted after query name lines.
              (commit bea9ce35b4177f407575ed0752c36bba8a50f502)

2009-02-03 Naohisa Goto <ng@bioruby.org>

            * Tutorial.rd.ja

              * Document bug: BioRuby shell commands seq, ent, obj were renamed to
                getseq, getent, getobj, respectively. Thanks to Hiroyuki Mishima
                who reports the issue ([BioRuby-ja]).
              * Changes of returned value of getseq are also reflected to the
                document.
              * Recommended Ruby version and installation procedure are also
                changed.
              (commit 916e96ca549db71a550e7a5d3bd49a3149614313)

            * doc/Changes-0.7.rd

              Documentation forgotten in 1.1.0: rename of BioRuby shell commands.
              (commit 64113314caac3453b4cc3b80ece9b5fb5841e069)

2009-01-30 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/blast/format0.rb

              Bug fix: incorrect parsing of hit sequence's whole length.
              (commit 98e6f57630b2c3394a9403f58e76b102346c56ef)

              Bug fix: Whole length of a hit sequence is mistakenly parsed when
              it contains ",". WU-BLAST parser is also affected in addition to
              NCBI BLAST parser.

            * lib/bio/db/lasergene.rb, lib/bio/db/soft.rb,
              lib/bio/util/color_scheme.rb, lib/bio/util/contingency_table.rb,
              lib/bio/util/restriction_enzyme.rb

              Removed ":nodoc:" in in "module Bio" which prevents RDoc of the
              Bio module.
              (commit 458db79b467d40ed02db0d085218f611e7dd5e04)

2009-01-29 Naohisa Goto <ng@bioruby.org>

            * doc/Changes-1.3.rdoc

              Added documents about Bio::TogoWS and Bio::BIORUBY_VERSION.

            * lib/bio/shell/plugin/entry.rb

              getent (BioRuby shell command) is changed to use EBI Dbfetch or
              TogoWS in addition to NCBI or KEGG API.
              (commit 0e172590f60dd5a5f27a24ecd230037a7909224c)

            * lib/bio/shell/plugin/togows.rb, lib/bio/shell.rb

              Added new shell plugin providing accesses to TogoWS REST services.
              (commit 03f6720b90e90703c23536a11b3f12c8155550ff)

            * lib/bio.rb

              Added autoload of Bio::TogoWS.
              (commit f8605e1234164a7aa7f236b4e96a4299229753d7)

            * test/functional/bio/io/test_togows.rb,
              test/unit/bio/io/test_togows.rb

              Newly added functional and unit tests for Bio::TogoWS::REST.
              (commit f04152b80d07f44f146fa3fa0729facede865aac)

            * lib/bio/io/togows.rb

              New class Bio::TogoWS::REST, a REST client for the TogoWS web
              service (http://togows.dbcls.jp/site/en/rest.html).
              (commit 652d2534163675182b9ce30cbb1dd5efff45cd60)

            * bin/br_pmfetch.rb

              Changed to use Bio::BIORUBY_VERSION_ID instead of CVS version ID.
              (commit f69d538ffa9ded00eb68dd306e65505d03b6c656)

            * lib/bio/shell/core.rb

              Changed to use BIORUBY_VERSION_ID.
              (commit 4ce11656a205e85cae64eca27cef7cd94eb80930)

            * bioruby.gemspec.erb

              Gem version is now determined from lib/bio/version.rb or
              BIORUBY_GEM_VERSION environment variable.
              (commit 1811e845e60bc2847ea5717ef936bad93f9f2c87)

            * Rakefile

              * Changed to use lib/bio/version.rb.
              * Environment variable BIORUBY_EXTRAVERSION is renamed to
                BIORUBY_EXTRA_VERSION.
              * Added dependency on lib/bio/version.rb to bioruby.gemspec.
                (commit fb27eaa584cda1bb4cb75e10085996503361c98a)

            * lib/bio.rb, lib/bio/version.rb

              Bio::BIORUBY_VERSION is split into lib/bio/version.rb.
              (commit 9779398c3fa0e9405a875b754a5243e0d6922c32)

              * New file lib/bio/version.rb contains BioRuby version information.
              * New constants: Bio::BIORUBY_EXTRA_VERSION stores extra version
                string (e.g. "-pre1") and Bio::BIORUBY_VERSION_ID stores BioRuby
                version string (e.g. "1.3.0-pre1").
              * Bio::BIORUBY_VERSION is changed to be frozen. Above two constants
                also store frozen values.

2009-01-26 Naohisa Goto <ng@bioruby.org>

            * KNOWN_ISSUES.rdoc

              Newly added KNOWN_ISSUES.rdoc that describes known issues and
              bugs in current BioRuby.
              (commit 06b10262be0bf797a3b133e4697e9b0955408944)
              (commit a65ad8b42613e46b0b4bb0650d6301da0dcc88c9)

            * lib/bio/shell/plugin/ncbirest.rb, lib/bio/shell.rb

              New shell plugin lib/bio/shell/plugin/ncbirest.rb, providing
              "efetch", "einfo", "esearch", and "esearch_count" methods.
              They act the same as those defined in Bio::NCBI::REST, except
              that "efetch" fetches entries with pre-defined databases
              depending on arguments.
              (commit c482e1864aa0dbca3727b1059d4fe3d0aefb3917)
              (commit 3360b8905fdbcd4ca050470fdb2f02a7387e8bb9)

            * lib/bio/shell/plugin/entry.rb

              Shell commands "getent" and "getseq" are changed to use
              "efetch" method when "gb" or some variant is specified as
              the database.
              (commit c482e1864aa0dbca3727b1059d4fe3d0aefb3917)
              (commit 3360b8905fdbcd4ca050470fdb2f02a7387e8bb9)

            * bioruby.gemspec.erb, bioruby.gemspec

              * Changed version to 1.2.9.9501.
              * Changed to use "git ls-files" instead of "git-ls-files", and
                changed not to redirect to /dev/null.
              * Special treatment of bioruby.gemspec is removed.
              * ChangeLog is included to RDoc.
              * Set RDoc title to "BioRuby API documentation".
              * Set "--line-numbers" and "--inline-source" to rdoc_options.
                (commit f014685090c38eeb64219603f2c7e90574849431)
              * added KNOWN_ISSUES.rdoc to files for no-git environment.
                (commit 06b10262be0bf797a3b133e4697e9b0955408944)
              * Ruby 1.9 support: command execution with shell can raise
                an error.
                (commit 3179de32f1dc746c8de975917b1718a523800d69)
              * bioruby.gemspec is generated from bioruby.gemspec.erb.
                (commit 4e1cd3bfb8207b357d5b71cc0fc8366f06491130)
                (commit 06b10262be0bf797a3b133e4697e9b0955408944)

2009-01-21 Naohisa Goto <ng@bioruby.org>

            * ChangeLog

              Added recent changes and fixed typo for recent changes.

2009-01-20 Naohisa Goto <ng@bioruby.org>

            * ChangeLog, doc/Changes-1.3.rdoc

              Added ChangeLog and doc/Changes-1.3.rdoc for recent changes.
              (commit be2254ddea152fddf51a2476eeb20d804b1e3123)

            * bioruby.gemspec

              Added bioruby.gemspec created from bioruby.gemspec.erb.
              (commit 4c54597eaf09107c34ad06bc5f5f9cead77a0198)

            * lib/bio/appl/blast/wublast.rb

              Bug fix: parsing of exit code failed when ignoring fatal errors
              (commit 44ed958acebe4324a9a48e7292c4f0ad5c0fb685)

              * Bug fix: could not get exit code in WU-BLAST results executed
                with a command line option "-nonnegok", "-novalidctxok", or
                "-shortqueryok".
              * New methods Bio::Blast::WU::Report#exit_code_message and #notes.

            * Rakefile

              Added package tasks and changed to use ERB instead of eruby.
              (commit 7b081c173d3b1cbc46034297ea802a4e06f85b2f)

            * bioruby.gemspec.erb

              Use git-ls-files command to obtain list of files when available.
              (commit 5d5cb24fdd56601bc43ee78facc255ca484245c0)

2009-01-17 Naohisa Goto <ng@bioruby.org>

            * Rakefile

              Simple Rakefile for dynamic generation of bioruby.gemspec
              (commit d5161d164f3520db25bed9aececb962428b9d6bc)

            * bioruby.gemspec.erb

              bioruby.gemspec is renamed to bioruby.gemspec.erb with modification.
              (commit bef311668e4a3be30965ce94d41e7bde4a4e17f9)

              To prevent the error "Insecure operation - glob" in GitHub,
              bioruby.gemspec is renamed to bioruby.gemspec.erb, and modified
              to generate the file list by using eruby.

2009-01-15 Naohisa Goto <ng@bioruby.org>

            * doc/Changes-1.3.rdoc

              Changes-1.3.rd is renamed to Changes-1.3.rdoc with format
              conversion, and fixed typo.
              (commit 1aef599650d14362ed233dcc9a7db8d3c1db1777)

              Added details about newly added classes etc.
              (commit eda9fd0abbb8e430810468d777d0b585e33c25d8)

2009-01-13 Naohisa Goto <ng@bioruby.org>

            * bioruby.gemspec

              Changed version to 1.2.9001, set has_rdoc = true and rdoc options.
              (commit 1f63d3d5389dd3b0316e9f312b56e62371caa253)

              * Gem version number changed to 1.2.9.9001 for testing gem.
              * Changed to has_rdoc = true.
              * README.rdoc and README_DEV.rdoc are now included to gem's rdoc,
                and README.rdoc is set to the main page.
              * *.yaml is now excluded from rdoc.

2009-01-13 Jan Aerts <jan.aerts@gmail.com>

            * bioruby.gemspec

              Renamed gemspec.rb to bioruby.gemspec because so github builds
              the gem automatically
              (commit 561ae16d20f73dcd6fc3d47c41c97c32f9aadb1a)
              (committer: Naohisa Goto)
              (original commit date: Wed Jun 25 11:01:03 2008 +0100)

              Edited gemspec because github returned an error while building gem.
              (commit f0d91e07550872c2f0d5835e496af1add7759d42)
              (committer: Naohisa Goto)
              (original commit date: Wed Jun 25 11:03:04 2008 +0100)

2009-01-13 Naohisa Goto <ng@bioruby.org>

            * README.rdoc

              Changed format from RD to RDoc with some additional URLs
              (commit cb8781d701f22cbaf16575bb237a9e0cbf8cd407)

              Clarified copyright of README.rdoc and BioRuby
              (commit acd9e6d6e6046281c6c9c03cff1021449b8e780f)

              Updated descriptions about RubyGems, and added Ruby 1.9 partial
              support
              (commit ff63658b255988bf0e7a9f5a2d1523d5104fe588)

2009-01-09 Naohisa Goto <ng@bioruby.org>

            * test/runner,rb

              Ruby 1.9.1 support: using alternatives if no Test::Unit::AutoRunner
              (commit 5df2a9dc0642d4f1e9a4398d6af908780d622a6e)

2009-01-05 Naohisa Goto <ng@bioruby.org>

            * lib/bio/db/fantom.rb

              Bug fix: incomplete cgi parameter escaping, and suppressing warnings.
              (commit 754d8815255a0f0db20df9dd74f9f146605d430e)

              * Bug fix: incomplete cgi parameter escaping for ID string in
                Bio::FANTOM.get_by_id (and Bio::FANTOM.query which internally
                calls the get_by_id method).
              * Warning message "Net::HTTP v1.1 style assignment found" when
                $VERBOSE=true is suppressed.
              * Removed obsolete "rescue LoadError" when require 'rexml/document'.

            * lib/bio/io/fetch.rb

              Bug fix: possible incomplete form key/value escaping.
              (commit ecaf2c66261e4ce19ab35f73e305468e1da412ed)

              * Bug fix: possible incomplete form key/value escaping
              * Refactoring: changed to use private methods _get and _get_single
                to access remote site.

            * lib/bio/io/pubmed.rb

              Bug fix: possible incomplete escaping of parameters, and
              suppressing warnings
              (commit 93daccabb1a82bb20e92798c1810182dfb836ba7)

              * Bug fix: possible incomplete string escaping of REST parameters
                in Bio::PubMed#query and #pmfetch.
              * Warning message "Net::HTTP v1.1 style assignment found" when
                $VERBOSE=true is suppressed.
              * Removed obsolete "unless defined?(CGI)".

            * lib/bio/command.rb, test/unit/bio/test_command.rb

              Bug fix: incomplete escaping in Bio::Command.make_cgi_params etc.
              (commit 17c8f947e5d94012921f9252f71460e9d8f593e3)

              * Buf fix: in Bio::Command.make_cgi_params and
                make_cgi_params_key_value, string escaping of form keys and values
                is incomplete.
              * Warning message "useless use of :: in void context" is suppressed
                when running test/unit/bio/test_command.rb with $VERBOSE=true.
              * Unit tests are added.

            * lib/bio/appl/, lib/bio/io/ (9 files)

              Suppress warning message "Net::HTTP v1.1 style assignment found"
              when $VERBOSE = true.
              (commit a2985eb1f3aed383f1b1b391f2184317c7fd21c7)

2009-01-02 Naohisa Goto <ng@bioruby.org>

            * README.rdoc

              Changing optional requirements, recommended Ruby version, and
              setup.rb credit.
              (commit a5462ab4bd403d2d833e5d6db26ae98ca763513c)

2008-12-30 Naohisa Goto <ng@bioruby.org>

            * README.rdoc

              Fixed grammar and spelling in README.rdoc, indicated by
              Andrew Grimm at git://github.com/agrimm/bioruby.git
              in Sun Sep 21 19:59:03 2008 +1000.
              (commit 446918037bff392b9c6bc6828720c585733a8f4b)

2008-12-30 Naohisa Goto <ng@bioruby.org>

            * lib/bio.rb

              Changed BIORUBY_VERSION to 1.3.0, which will be the next BioRuby
              release version number.
              (commit b000b1c4a5a136ab287b517b8b8c66e54f99a8a8).

            * doc/Changes-1.3.rd

              Added documents about changed points for 1.3.0 release.
              (commit 028e323e784eb60b18f941cce1e3752abff1433c)

            * lib/bio/appl/blast/format8.rb

              Ruby 1.9 support: String#each_line instead of String#each
              (commit 1bc59708137fd46911d5892e4712cc49c71fa031)

            * lib/bio/io/flatfile/splitter.rb

              Checks for undefined constants are added for running without
              "require 'bio'" in unit tests.
              (commit 311176d4d390e5948348f623ff3632454136a03f)

            * lib/bio/appl/blast.rb, lib/bio/appl/blast/report.rb,
              test/unit/bio/appl/test_blast.rb

              Support for default (-m 0) and tabular (-m 8) formats in
              Bio::Blast.reports.

              * Added support for default (-m 0) and tabular (-m 8) formats in
                Bio::Blast.reports method. For the purpose, Bio::Blast::Report_tab
                is added to read tabular format by using Bio::FlatFile.
              * Unit tests are added.

2008-12-26 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/paml/codeml/rates.rb

              Ruby 1.9 support: String#each_line instead of String#each
              (commit 1789a3975c4c82d3b45f545893be8f2a7bf47a01)

2008-12-26 Naohisa Goto <ng@bioruby.org>

            * lib/bio/command.rb, lib/bio/appl/fasta.rb,
              lib/bio/appl/blast/genomenet.rb

              Refactoring and following the change of the remote site
              fasta.genome.jp.
              (commit 671092dff67890fc48dd7ff2f606c4cedc2eb02c)

              * New method Bio::Command.http_post_form.
              * Bio::Blast::Remote::GenomeNet#exec_genomenet and
                Bio::Fasta#exec_genomenet are changed to use the new method.
              * Changed a regexp. in Bio::Fasta#exec_genomenet is changed
                following the change of the remote GenomeNet (fasta.genome.jp).

2008-12-24 Naohisa Goto <ng@bioruby.org>

            * lib/bio/location.rb, test/unit/bio/test_location.rb

              New method Bio::Locations#to_s with bug fix, etc.
              (commit 115b09456881e1d03730d0b9e7a61a65abf6a1fe)

              * New method Bio::Locations#to_s is added.
              * New attributes Bio::Locations#operator and Bio::Location#carat.
              * Changed not to substitute from "order(...)" or "group(...)" to
                "join(...)".
              * Bug fix: Bio::Locations.new(str) changes the argument string
                when the string contains whitespaces.
              * Unit tests for Bio::Locations#to_s are added.

2008-12-20 Naohisa Goto <ng@bioruby.org>

            * test/functional/bio/appl/test_pts1.rb,
              test/unit/bio/appl/test_pts1.rb

              Moved part of test_pts1.rb using network from test/unit to
              test/functional.
              (commit 933ff3e7d615fe6521934f137519ea84b3b517f2)

2008-12-18 Naohisa Goto <ng@bioruby.org>

            * test/unit/bio/io/test_soapwsdl.rb

              Ruby 1.9 support: following the change of Object#instance_methods
              (commit 008cf5f43786f6143f74889e0ec53d1c8a452aa2)

              Note that SOAP/WSDL library is no longer bundled with Ruby 1.9,
              and tests in test_soapwsdl.rb may fail.

            * test/unit/bio/io/test_ddbjxml.rb

              Ruby 1.9 support: following the change of Module::constants
              (commit ed1ad96e7ed9d6c7d67e5413a22ba935a3b36efa)

            * lib/bio/util/restriction_enzyme/single_strand.rb

              Ruby 1.9 support: changed Array#to_s to join, Symbol#to_i to __id__,
              etc.
              (commit a29debb8c03244c1ce61317d6df0a2c5d066de3d)

              * Ruby 1.9 support: in pattern method, changed to use Array#join
                instead of Array#to_s.
              * Ruby 1.9 support: in self.once method, changed to use
                Object#__id__ instead of Symbol#to_i.
              * self.once is changed to be a private class method.

2008-12-18 Naohisa Goto <ng@bioruby.org>

            * lib/bio/db/rebase.rb

              Ruby 1.9 support: changed not to use String#each, etc.
              (commit 47ba6e9fcf864f5881211e766f2e47b60dde178a)

              * Ruby 1.9 support: In parse_enzymes, parse_references, and
                parse_suppliers methods, String#each is changed to each_line.
              * Changed to use require instead of autoload, to reduce support cost.

2008-12-16 Moses Hohman <moses@moseshohman.com>

            * lib/bio/db/medline.rb, test/unit/bio/db/test_medline.rb

              fix medline parsing of author last names that are all caps
              (commit 5f37d566fc2efa4878efbd19e83f909a58c4cb00)

2008-12-15 Mitsuteru Nakao <n@bioruby.org>

            * lib/bio/db/kegg/glycan.rb

              Bug fix in Bio::KEGG::GLYCAN#mass.
              Thanks to a reporter.
              (commit cb8f1acc4caebf1f04d4a6c141dd4477fcb5394b)
              (committer: Naohisa Goto)

2008-12-15 Naohisa Goto <ng@bioruby.org>

            * lib/bio/pathway.rb, test/unit/bio/test_pathway.rb

              Fixed pending bugs described in unit test, and Ruby 1.9 support
              (commit 97b3cd4cf78eff8aede16369298aaacf1c319b68)

              * Pending bugs described in test/unit/bio/test_pathway.rb are fixed.
                Fixed a bug in subgraph: does not include nodes w/o edges.
                A bug in cliquishness depending on the subgraph bug is also fixed.
              * Bio::Pathway#cliquishness is changed to calculate cliquishness
                (clustering coefficient) for not only undirected graphs but also
                directed graphs. Note that pending proposed specification changes
                previously written in test_pathway.rb (raises error for directed
                graphs, and return 1 for a node that has only one neighbor node)
                are rejected.
              * Ruby 1.9 support: To avoid dependency to the order of objects
                in Hash#each (and each_keys, etc.), Bio::Pathway#index is used
                to specify preferences of nodes in a graph. Affected methods
                are: to_matrix, dump_matrix, dump_list, depth_first_search.
              * Bug fix in the libpath magic in test/unit/bio/test_pathway.rb.

2008-12-09 Naohisa Goto <ng@bioruby.org>

            * lib/bio/db/newick.rb, lib/bio/tree.rb

              Ruby 1.9 support: suppressing "warning: shadowing outer local
              variable".
              (commit 6fe31f0a42a87631bdee3796cff65afb053b2add)

2008-12-05 Naohisa Goto <ng@bioruby.org>

            * test/unit/bio/io/test_fastacmd.rb

              Ruby 1.9 support: changed to use respond_to?, etc.
              (commit 5d6c92c752c00f07ed856fd209c8078ef9fdf57a)

              * Following the change of Module#methods in Ruby 1.9, changed
                to use respond_to?().
              * The test path '/tmp/test' is replaced with '/dev/null'

            * lib/bio/db/gff.rb

              Ruby 1.9 support: changes following the change of String#[]
              (commit c25cc506bffcf1f2397ac2210153cfbfbbcb4942)

            * lib/bio/reference.rb

              Ruby 1.9 support: using enumerator instead of String#collect
              (commit ea99242570fc8b2e2a869db84b7daaa7737f23e0)

            * test/unit/bio/test_location.rb

              Test bug fix: wrong number in libpath magic
              (commit aa45101246bc42f78a21ee110bc58e59f532e24a)

            * test/unit/bio/db/test_nexus.rb

              Test bug fix: missing libpath magic
              (commit d54eed426461f3a3148953fda1f7b428e74051c6)

              Thanks to Anthony Underwood who reports the bug in his Github
              repository.

            * test/unit/bio/db/pdb/test_pdb.rb

              Test bug fix: wrong number in libpath magic
              (commit b53d703a8dd72608ab5ea03457c2828470069f2f)

2008-12-04 Naohisa Goto <ng@bioruby.org>

            * test/unit/bio/db/embl/test_embl_to_bioseq.rb

              Test bug fix: typing error (found by using Ruby 1.9)
              (commit fa52f99406ddd42221be354346f67245b3572510)

            * test/unit/bio/db/embl/test_common.rb

              Ruby 1.9 support: following the change of Module#instance_methods
              (commit d18fa7c1c3660cf04ec2a8a42d543a20a77cee2c)

              In Ruby 1.9, Module#instance_methods returns Array containing
              Symbol objects instead of String. To support both 1.8 and 1.9,
              "to_s" is added to every affected test method.

            * lib/bio/appl/tmhmm/report.rb

              Ruby 1.9 support: using enumerator if the entry is a string
              (commit 36968122b64b722e230e3e1b52d78221c0b60884)

            * lib/bio/appl/pts1.rb

              Ruby 1.9 support: String#each to each_line and Array#to_s to join('')
              (commit c4c251d5e94167512a0b8a38073a09b72994c08f)

            * test/unit/bio/appl/test_fasta.rb

              Ruby 1.9 support: changed to use Array#join instead of Array#to_s
              (commit bf8823014488166c6e1227dd26bdca344c9f07b7)

            * lib/bio/appl/blast.rb

              Ruby 1.9 support: String#each is changed to String#each_line
              (commit 3e177b9aecf6b54a5112fd81fc02386d18fc14b9)

            * lib/bio/appl/hmmer/report.rb

              Ruby 1.9 support: String#each is changed to String#each_line
              (commit 63bdb3a098bc447e7bd272b3be8f809b4b56d451)

            * lib/bio/appl/genscan/report.rb

              Ruby 1.9 support: String#each is changed to String#each_line
              (commit 082250786756de2b4171b3a00e0c4faaa816fc8f)

            * test/functional/bio/io/test_ensembl.rb

              Using jul2008.archive.ensembl.org for workaround of test failure.
              (commit 1d286f222cdc51cf1323d57c1c79e6943d574829)

              Due to the renewal of Ensembl web site, lib/bio/io/ensembl.rb
              does not work for the latest Ensembl. For a workaround of
              the failure of tests in test/functional/bio/io/test_ensembl.rb,
              tests for Ensembl#exportview are changed using Ensembl archive
              (http://jul2008.archive.ensembl.org/).

2008-12-03 Naohisa Goto <ng@bioruby.org>

            * sample/demo_sequence.rb

              sample/demo_sequence.rb, example of sequence manipulation.
              (commit b7f52b47dbcc7d32f4eb7377d2b1510eb1991fd5)

              The content of this file is moved from previous version of
              lib/bio/sequence.rb (inside the "if __FILE__ == $0").

2008-12-02 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/paml/baseml.rb, etc. (17 files)

              Support for baseml and yn00 (still under construction), and
              incompatible changes to Bio::PAML::Codeml.
              (commit d2571013409661b4d7be8c5c9db14dbe9a9daaaf)

              * Security fix: To prevent possible shell command injection,
                changed to use Bio::Command.query_command instead of %x.
              * Bug fix with incompatible changes: Using Tempfile.new.path
                as default values are removed because this can cause
                unexpected file loss during garbage collection.
              * Change of method/file names: The term "config file" is changed
                to "control file" because the term "config file" is never used
                in PAML documents. The term "options" is changed to "parameters"
                because the "options" have been used for command-line arguments
                in other wrappers (e.g. Bio::Blast, Bio::ClustalW). The term
                "parameters" is also used in BioPerl's
                Bio::Tools::Run::Phylo::PAML.
              * Bio::PAML::Codeml.create_config_file, create_control_file,
                Bio::PAML::Codeml#options, and #options= are now deprecated.
                They will be removed in the future.
              * New class Bio::PAML::Common, basic wrapper common to PAML programs.
                Bio::PAML::Codeml is changed to inherit the Common class.
              * New classes Bio::PAML::Baseml and Bio::PAML::Yn00, wrappers for
                baseml and yn00.
              * New classes Bio::PAML::Common::Report, Bio::PAML::Baseml::Report
                and Bio::PAML::Yn00::Report, but still under construction.
              * New methods Bio::PAML::Codeml#query(alignment, tree), etc.
              * test/data/paml/codeml/dummy_binary is removed because
                the default of Bio::PAML::Codeml.new is changed to use
                "codeml" command in PATH.
              * test/data/paml/codeml/config.missing_tree.txt is removed
                because treefile can be optional parameter depending on runmode.
                test/data/paml/codeml/config.missing_align.txt is also removed
                because test is changed to use normal control file parameters.

            * lib/bio/command.rb, test/functional/bio/test_command.rb

              Improvement of Bio::Command.query_command, call_command, etc.
              (commit e68ee45589f8063e5a648ab235d6c8bbc2c6e5ff)

              * Improvement of Bio::Command.query_command, call_command,
                query_command_popen, query_command_fork, call_command_popen,
                and call_command_fork: they can get an option :chdir => "path",
                specifying working directory of the child process.
              * New method Bio::Command.mktmpdir backported from Ruby 1.9.0.
              * New method Bio::Command.remove_entry_secure that simply calls
                FileUtils.remove_entry_secure or prints warning messages.
              * Tests are added in test/functional/bio/test_command.rb.
              * Ruby 1.9 followup: FuncTestCommandQuery#test_query_command_open3
                failed in ruby 1.9 due to the change of Array#to_s.

2008-11-19 Naohisa Goto <ng@bioruby.org>

            * test/data/paml/codeml/

              Removed some files in test/data/paml/codeml/ because of potential
              copyright problem, because they are completely identical with
              those distributed in PAML 4.1.
              (commit 086b83d3e54f69d2b9e71af3f9647518768353b0)

2008-10-21 Naohisa Goto <ng@bioruby.org>

            * lib/bio/sequence/compat.rb

              Bug fix: TypeError is raised in Bio::Sequence#to_s before
              Sequence#seq is called.
              (commit ea8e068a5b7f670ce62bc0d3d4b21639e3ca2714)

              Thanks to Anthony Underwood who reported the bug and sent the patch.

2008-10-19 Naohisa Goto <ng@bioruby.org>

            * setup.rb, README.rdoc

              install.rb is replaced by new setup.rb.
              (commit 9def7df5b81340c49534ff0bb932de62402a1c8d)

              * install.rb is replaced by the latest version of setup.rb taken
                from the original author's svn repository (svn r2637, newer than
                version 3.4.1, latest release version.
                $ svn co http://i.loveruby.net/svn/public/setup/trunk setup).
              * README.rdoc is modified to follow the rename of install.rb to
                setup.rb.

2008-10-18 Toshiaki Katayama <k@bioruby.org>

            * lib/bio/io/ncbirest.rb

              * New methods: Bio::NCBI::REST#einfo, #esearch_count, etc.
              * New classes: Bio::NCBI::REST::ESearch, Bio::NCBI::REST::EFetch.
              (commit 637f97deefd6cc113ef18fe18ab628eb619f3dc1)
              (committer: Naohisa Goto)

2008-10-14 Naohisa Goto <ng@bioruby.org>

            * lib/bio/sequence/common.rb, test/unit/bio/sequence/test_common.rb,
              test/unit/bio/sequence/test_compat.rb,
              test/unit/bio/sequence/test_na.rb

              Bug fix: Bio::Sequence::Common#randomize severely biased.
              (commit 02de70cbf036b41a50d770954f3b16ba2beca880)

              * Bug fix: Bio::Sequence::Common#randomize was severely biased.
                To fix the bug, it is changed to used Fisher-Yates shuffle,
                as suggested by Anders Jacobsen.
                ([BioRuby] Biased Bio::Sequence randomize())
              * The module method Bio::Sequence::Common.randomize is removed
                because it is not used anymore.
              * Unit tests for Bio::Sequence::Common#randomize are added.
              * To avoid possible test class name conflicts, class/module
                names are changed in test_na.rb, test_compat.rb, and
                test_common.rb.

2008-10-14 Raoul Jean Pierre Bonnal <raoul.bonnal@itb.cnr.it>

            * lib/bio/io/sql.rb

              Changed the demonstration code in the "if __FILE__ == $0".
              (commit 9942105920182c809564554bb0d1dba33fe4caab)

            * lib/bio/db/biosql/sequence.rb

              Fix: typing error
              (commit 67fbbb93adaa8b4b91de3703a235bc75eaef842a)

2008-10-14 Naohisa Goto <ng@bioruby.org>

            * lib/bio/db/biosql/sequence.rb, lib/bio/io/sql.rb

              Merging patches by Raoul in commit
              496561a70784d3a1a82bf3117b2d267c7625afac which are ignored
              when rebasing, probably because of manually editing during merge.
              (commit c699253d53510c0e76188a72004651a4635088b3)

2008-10-10 Raoul Jean Pierre Bonnal <raoul.bonnal@itb.cnr.it>

            * lib/bio/db/biosql/sequence.rb

              Fix: check on nil objects (to_biosql)
              (commit f701e9a71f524ee4373c94ee1bd345e87f16f6ce)

              BugFix: ex. /focus="true" in output was /focus="t",
              qualifier.value.to_s fix the bug
              (commit f6e1530f3372c87031b551e5c76e24f264891e64)

            * lib/bio/io/biosql/seqfeature.rb

              BugFix: seqfeature_qualifier_value returned ordered only by rank
              (commit fb74009393eeca6743f78b7b45cb66858c41d733)

            * lib/bio/io/biosql/bioentry.rb

              BugFix: seqfeatures returned ordered by rank
              (commit 25a249d87d23bd9cb4e671053019675836fcd38c)

            * lib/bio/db/biosql/sequence.rb

              Fixed to suppress warnings: Bio::Features is obsoleted.
              (commit 198a1e893dd4515d61276c9cce8905f02130e721)

            * lib/bio/db/biosql/biosql_to_biosequence.rb

              Removed alias comment.
              (commit c037ec565987634b354ff6d77dbbe7c9d83a9e7c)

            * lib/bio/db/biosql/sequence.rb

              Implemented Entry's comments and reference's comments.
              Fixed species common name.
              (commit bd3b24ea53ebd9b0ec9dd9f15c27091fe6143e28)

            * lib/bio/io/biosql/bioentry.rb

              Cleaned, deleted pk and seq reference
              (commit 14bcf90334ec3c3f1c1784977b329ae641e9e106)

            * lib/bio/io/biosql/comment.rb

              cleaned codes
              (commit 54976693350ab0512cecf946999c2868b9e88007)

            * lib/bio/db/biosql/biosql_to_biosequence.rb

              Added comments, comment adapter.
              (commit 5394ecea34778c9f571eb35cfc16e3b1a6cb6d1b)

2008-10-09 Raoul Jean Pierre Bonnal <raoul.bonnal@itb.cnr.it>

            * lib/bio/io/sql.rb

              Changed the demonstration code in the "if __FILE__ == $0".
              (commit efb61d7c21d229e882c6706838c284404343fa9c)

            * lib/bio/db/biosql/sequence.rb

              Added support for reference. ToDo: handling comments.
              (commit 29211059ee04214d7879f900ec563c0708d8c9d6)

            * lib/bio/io/biosql/bioentry_reference.rb

              Fix: compisite primary keys :bioentry_id, :reference_id, :rank
              (commit eba61ba670c591f58866b37ababc4acac0cc7883)

            * lib/bio/io/biosql/dbxref.rb

              removed explicit pk and seq
              (commit e149f94484469fb3dfd881b45b14be7093b67e0d)

2008-10-09 Naohisa Goto <ng@bioruby.org>

            * test/functional/bio/test_command.rb,
              test/data/command/echoarg2.bat

              Bug fix: tests in FuncTestCommandCall are failed on mswin32,
              and URL changed.
              (commit 921292f1188d85994742ce4aa156b39d6e720aad)

              * Bug fix: tests in FuncTestCommandCall were failed on mswin32.
                To fix the test bug, a batch file test/data/command/echoarg2.bat
                is newly added. This file is only used on mswin32 or bccwin32.
              * URL for test to fetch a web page is changed to
                http://bioruby.open-bio.org/.

2008-10-07 Naohisa Goto <ng@bioruby.org>

            * test/unit/bio/appl/paml/test_codeml.rb

              Bug fix: error on mswin32 in
              test_expected_options_set_in_config_file.
              (commit  16b8f321c653502ef801d801383a019bc45f67de)

              Bug fix: On mswin32, test_expected_options_set_in_config_file
              in Bio::TestCodemlConfigGeneration failed with the error
              "Errno::EACCESS: Permission denied" because it attempts to remove
              the temporary file that is previously opened but not explicitly
              closed, and, in Windows, the opend file is automatically locked
              and protected from being removed.

            * lib/bio/command.rb, test/functional/bio/test_command.rb,
              test/unit/bio/test_command.rb

              Bio::Command improved, and added functional tests.
              (commit bb618cdfbfb56c40249aff81b6ef84742465851c)

              * In Bio::Command.call_command_* and Bio::Command.query_command_*,
                when giving command-line array with size 1, the command might
                passed to shell. To prevent this, changed to call a new method
                Bio::Command#safe_command_line_array internally.
              * Added test/functional/bio/test_command.rb, contains unit tests
                to call external commands and to access external web sites.

2008-10-06 Naohisa Goto <ng@bioruby.org>

            * lib/bio/db/biosql/sequence.rb

              Bio::Sequence::SQL::Sequence#seq is changed to return a
              Bio::Sequence::Generic object, because of avoiding to create
              nested Bio::Sequence object in #to_biosequence and because
              Bio::FastaFormat#seq also returns a Bio::Sequence::Generic object.
              (commit 8fb944c964ab5e1ca8905e6c4ce8e68479952935)

2008-10-03 Raoul Jean Pierre Bonnal <raoul.bonnal@itb.cnr.it>

            * lib/bio/io/biosql/taxon.rb

              Added has_one :taxon_genbank_common_name,
              :class_name => "TaxonName",
              :conditions => "name_class = 'genbank common name'"
              (commit dc7a18b17cad8e603e0d3c20a5a80bc2a6f0899c)

            * lib/bio/db/biosql/sequence.rb

              Fix taxon identification by splitting scientific name and genbank
              common name. Fix organism/source's name composed by scientific
              name and genbank common name.
              (commit 5d6abcc0dcd05d7083622360489a5f4c361e0cc7)

            * lib/bio/io/sql.rb

            Working on tests about format import/export.
            (commit d28a343e4bab3cc0c04ac65dce677cfee0f81a46)

            * lib/bio/io/biosql/term.rb

              Fix foreign keys
              (commit c19c8766c7c0bec7561727abf2ef1bdf47d4e032)

            * lib/bio/io/biosql/seqfeature_qualifier_value.rb

              added composite primary keys :seqfeature_id, :term_id, :rank
              (commit cdd6a3bfc1ab748acb0c0d9161ebeb3dc7a76544)

            * lib/bio/io/biosql/ontology.rb

              class cleaned.
              (commit 81eb2c246d01790db72f0b08929bec5d862c959e)

            * lib/bio/io/biosql/biodatabase.rb

              class cleaned.
              (commit 4aede5c5fee92c2f8cdf151a3e038025b6c7fd74)

            * lib/bio/db/biosql/sequence.rb

              to_biosequence: removed not adapter comments.
              (commit 591fda23464c7b7031db09a8ca85deca320a5c87)

              Removed main garbage comments.
              (commit c46d7a2b4e188a0592d5b49def17b9e6fd598268)

              feature= Fix creation of Ontology and Term.
              (commit 95fe6d1a65e94da502529e597b137d12c3fe2fc2)

            * lib/bio/db/biosql/biosql_to_biosequence.rb

              :seq cleaned.
              (commit d6f719693286b74c1a0ea8a42c09a12f775b74dc)

2008-10-01 Naohisa Goto <ng@bioruby.org>

            * test/functional/bio/io/test_ensembl.rb

            Bug fix: 3 failures occurred in test_ensembl.rb because of recent
            changes in Ensembl database (the gene ENSG00000206158 used as
            an example in this file was removed from the Ensembl database).
            To fix this, the example gene is changed to ENSG00000172146
            (OR1A1, olfactory receptor 1A1).
            (commit e20c86d2cd7d4fd1723762e8a5acc3bc311a5c1b)

            * lib/bio/db/embl/sptr.rb, test/unit/bio/db/embl/test_sptr.rb

              Ruby 1.9 support: in Bio::SPTR, avoid using String#each and
              Array#to_s.
              (commit 5ff56653cd7cc2520c2c04acbc9ce2bf2a0fae9a)

              * In Bio::SPTR#gn_uniprot_parser, String#each (which is removed
                in Ruby 1.9) is changed to each_line.
              * In Bio::SPTR#cc and cc_* (private) methods, Array#to_s (whose
                behavior is changed in Ruby 1.9) is changed to join('').
              * Unit test for Bio::STPR#dr method is added and changed.

2008-09-30 Naohisa Goto <ng@bioruby.org>

            * lib/bio/db/embl/sptr.rb, test/unit/bio/db/embl/test_sptr.rb

              Bug fix in Bio::SPTR#dr: raised error when asked it to return
              a DR key that didn't exist in the uniprot entry. Thanks to
              Ben Woodcroft who reports the bug and send a patch.
              ([BioRuby] Bio::SPTR bug and fix).
              (commit 3147683c0b41e3f9418e26b481bf8b3e9ce63b8c)

            * lib/bio.rb

              Added autoload of Bio::NCBI::REST, and BIORUBY_VERSION incremented.
              (commit d6a37b0fcf1fb2f6e134dcdb8e29e79ec2a8fea7)

              * Added autoload of Bio::NCBI::REST.
              * Added comments for autoloading Bio::Sequence and Bio::Blast.
              * BIORUBY_VERSION is temporary incremented to 1.2.2, though
                the version number will not be used in upcoming release.
                Upcoming release will probably be using larger version number.

2008-09-25 Raoul Jean Pierre Bonnal <raoul.bonnal@itb.cnr.it>

            * lib/bio/db/biosql/sequence.rb

              Updated with adapter. Problem saving big sequences.
              (commit 82d87fbaf70f9a46c40dded0b2db510a40964e62)

            * lib/bio/io/biosql/* (25 files)

              AR: explicit class and foreign_key reference.
              (commit 70327998186c2f943addb5d46b4bda8007ed5444)

2008-09-24 Naohisa Goto <ng@bioruby.org>

            * lib/bio/db/gff.rb, test/unit/bio/db/test_gff.rb

              Bug fix and incompatible changes in GFF2 and GFF3 attributes.
              (commit 7b174bb842d9dcf9fd7f4b59e8f3b13ebc0ff3d4)

              * Bug fix: GFF2 attributes parser misunderstand semicolons.
              * Incompatible change in Bio::GFF::GFF2::Record#attributes
                and Bio::GFF::GFF3::Record#attributes.  Now, instead of Hash,
                the method is changed to return a nested Array, containing
                [ tag, value ] pairs, because of supporting multiple tags
                in same name.  If you want to get a Hash, use
                Record#attributes_to_hash method, though some tag-value pairs
                in same tag name may not be included.
              * Bio::GFF::Record#attribute still returns a Hash for compatibility.
              * New methods for getting, setting and manipulating attributes:
                Bio::GFF::GFF2::Record#attribute, #get_attribute, #get_attributes,
                #set_attribute, #replace_attributes, #add_attribute,
                #delete_attribute, #delete_attributes, and #sort_attributes_by_tag!
                (These are also added to Bio::GFF::GFF3::Record).
                It is recommended to use these methods instead of directly
                manipulating the array returned by Record#attributes.
                * Incompatible change in GFF2 attributes parser: the priority
                of '"' (double quote) is greater than ';' (semicolon).
                Special treatment of '\;' in GFF2 is now removed.
                Unlike GFF2, in Bio::GFF, the '\;' can still be used for
                backward compatibility.
              * Incompatible changes in attribute values in Bio::GFF::GFF2.
                Now, GFF2 attribute values are automatically unescaped.
                In addition, if a value of an attribute is consisted of two
                or more tokens delimited by spaces, an object of the new class
                Bio::GFF::GFF2::Record::Value is returned instead of String.
                The new class Bio::GFF::GFF2::Record::Value aims to store
                a parsed value of an attribute.  If you really want to get
                unparsed string, Value#to_s can be used.
              * Incompatible changes about data type in GFF2 columns:
                Bio::GFF::GFF2::Record#start, #end, and #frame return
                Integer or nil, and #score returns Float or nil.
              * Incompatible changes about the metadata in GFF2.
                The "##gff-version" line is parsed and the version string
                is stored to Bio::GFF::GFF2#gff_version. Other metadata
                lines are stored in an array obtained with a new method
                Bio::GFF::GFF2#metadata. Each metadata is parsed to
                Bio::GFF::GFF2::MetaData object.
              * Bio::GFF::Record#comments is renamed to #comment, and
                #comments= is renamed to #comment=, because they only allow
                a single String (or nil) and the plural form "comments"
                may be confusable. The "comments" and "comments=" methods
                can still be used, but warning messages will be shown
                when using in GFF2::Record and GFF3::Record objects.
              * New methods Bio::GFF::GFF2#to_s, Bio::GFF::GFF2::Record#to_s.
              * New methods Bio::GFF::GFF2::Record#comment_only?
                (also added in Bio::GFF::GFF3::Record).
              * Unit tests are added and modified.

2008-09-18 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/blast/rpsblast.rb, lib/bio/appl/blast/format0.rb,
              lib/bio/io/flatfile/autodetection.rb,
              test/unit/bio/appl/blast/test_rpsblast.rb,
              test/data/rpsblast/misc.rpsblast

              Improved support for RPS-BLAST results from multi-fasta query
              sequences.
              (commit 11f1787cf93c046c06d4a33a554210d56866274e)

              * By using Bio::FlatFile (e.g. Bio::FlatFile.open), a rpsblast
                result generated from multiple query sequences is automatically
                split into multiple Bio::Blast::RPSBlast::Report objects
                corresponding to query sequences. For the purpose, new
                flatfile splitter class Bio::Blast::RPSBlast::RPSBlastSplitter
                is added.
              * File format autodetection for RPS-BLAST default report is added.
              * Bug fix: Bio::Blast::RPSBlast::Report#program returns incorrect
                value. To fix the bug, regular expression in
                Bio::Blast::Default::Report#format0_parse_header (private method)
                is changed.
              * Unit tests are added for Bio::Blast::RPSBlast.

2008-09-17 Naohisa Goto <ng@bioruby.org>

            * lib/bio/io/flatfile/buffer.rb,
              test/unit/bio/io/flatfile/test_buffer.rb

              Bug fix in Bio::FlatFile::BufferedInputStream#gets.
              (commit e15012e2a94d05308d139cb010749a1829d5c57f)

              * Bug fix: Bio::FlatFile::BufferedInputStream#gets('') might not
                work correctly. Now, BufferedInputStream#gets is refactored.
                Note that when rs = '' (paragraph mode), the behavior may still
                differ from that of IO#gets('').
              * Test methods are added to test_buffer.rb.

2008-09-16 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/blast/wublast.rb

              Bug fix: parse error or infinite loop for WU-BLAST reports.
              (commit 07d1554c945400f9202d7b856055743e11860752)

              * Bug fix in Bio::Blast::WU::Report: fixed parse errors
                (errors, infinite loop, and wrong results could be generated)
                when parsing WU-BLAST reports generated by recent version of
                WU-BLAST.
                * New methods Bio::Blast::WU::Report#query_record_number,
                  #exit_code, and #fatal_errors.

2008-09-03 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/blat/report.rb

              Bug fix: headers were parsed incorrectly with warning.
              (commit 3ff940988b76bdff75679cdf0af4c836f76fa3a1)

            * lib/bio/io/flatfile/splitter.rb

              To suppress warning messages "warning: private attribute?",
              private attributes are explicitly specified by using "private".
              (commit 1440b766202a2b66ac7386b9b46928834a9c9873)

2008-09-01 Michael Barton <mail@michaelbarton.me.uk>

            * lib/bio/appl/paml/codeml/report.rb

            Added code to pull estimated tree from codeml report.
            (commit 64cc5ef6f2d949cc9193b08dfc3fde6b221950d7)

2008-09-01 Naohisa Goto <ng@bioruby.org>

            * test/unit/bio/db/embl/test_embl_rel89.rb

              Changed test class name because of name conflict of Bio::TestEMBL.
              (commit 536cdf903a3c3908c117efd554d33117d91452f4)

            * test/unit/bio/util/restriction_enzyme/

              To prevent possible test class name conflicts about restriction
              enzyme.
              (commit 0fe1e7d3ed02185632f4a34d8efe1f21f755b289)

              * Tests about restriction enzyme are moved under a new module
                Bio::TestRestrictionEnzyme to prevent possible name conflict.
              * Conflicted test class names are changed.

2008-08-31 Naohisa Goto <ng@bioruby.org>

            * test/unit/bio/db/test_prosite.rb

              Fixed failed test due to the change of hash algorithm in Ruby 1.8.7.
              (Probably also affected in Ruby 1.9.0).
              (commit e86f8d757c45805389e154f06ccde5a3d9e8a557)

2008-08-29 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/blast.rb

              Bio::Blast.reports is changed to support new BLAST XML format.
              (commit 02cc0695b85f18e8254aefed78a912812fc896d6)

              * Bio::Blast.reports is changed to support new BLAST XML format.
              * Removed unused require.

2008-08-28 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/blast/report.rb, lib/bio/appl/blast/rexml.rb,
              lib/bio/appl/blast/xmlparser.rb,
              test/unit/bio/appl/blast/test_report.rb

              Support for BLAST XML format with multiple queries after blastall
              2.2.14.
              (commit de7897b5690279aae14d9bded5e682458bc61f9c)

              * BLAST XML format with multiple query sequences generated by
                blastall 2.2.14 or later is now supported.
              * New methods Bio::Blast::Report#reports, stores Bio::Blast::Report
                objects corresponding to the multiple query sequences.
              * New methods Bio::Blast::Report::Iteration#query_id, query_def,
                and query_len, which are available only for the new format.
              * New class Bio::Blast::Report::BlastXmlSplitter, flatfile splitter
                for Bio::FlatFile system.
              * Bug fix: Bio::Blast::Report#expect returned incorrect value.
              * Fixed typo and added tests in
                test/unit/bio/appl/blast/test_report.rb.
              * Some RDoc documents are added/modified.

2008-08-19 Michael Barton <mail@michaelbarton.me.uk>

            * lib/bio/appl/paml/codeml/rates.rb

              Updated regex for rates parser to include columns that have a '*'
              character.

            * test/unit/bio/appl/paml/codeml/test_rates.rb

              Updated testing for new rates file with * characters.

            * test/data/paml/codeml/rates

              Added rates file that includes positions with * characters.

2008-08-18 Naohisa Goto <ng@bioruby.org>

            * test/unit/bio/io/test_ddbjxml.rb

              Changed a failed test, and added a test for
              Bio::DDBJ::XML::RequestManager.

2008-08-16 Michael Barton <mail@michaelbarton.me.uk>

            * lib/bio/appl/paml/, test/unit/bio/appl/paml/, test/data/paml/

              Wrapper and parser for PAML Codeml program is added
              (merged from git://github.com/michaelbarton/bioruby).
              After merging, some changes were made by Naohisa Goto.
              See git log for details.

2008-08-15 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/blast.rb, lib/bio/appl/blast/genomenet.rb

              "-m 0" (BLAST's default) format support is improved, and fixed
              wrong example in the RDoc of Bio::Blast#query.

              * Added support for "-m 0" (BLAST's default) format to the Bio::Blast
                factory. For the purpose, Bio::Blast#parse_result (private method)
                is changed.
              * Added support for "-m 0" (default) format to the GenomeNet BLAST
                factory (in Bio::Blast::Remote::GenomeNet).
              * Bug fix: wrong example in the RDoc in Bio::Blast#query is changed.
              * Bio::Blast#set_option (private method) is changed to determine
                format correctly.

            * lib/bio/appl/blast/ddbj.rb, lib/bio/io/ddbjxml.rb

              Changed always using REST version of RequestManager, and changed
              to raise error when busy.

              * In Bio::Blast::Remote::DDBJ, changed always to use REST version
                for RequestManager, because of suppressing warning messages.
              * In Bio::DDBJ::XML::RequestManager, module REST_RequestManager is
                changed to class REST.
              * In Bio::Blast::Remote::DDBJ#exec_ddbj, changed to raise
                RuntimeError when "The search and analysis service by WWW is very
                busy now" message is returned from the server (which implies
                invalid options or queries may be given).

2008-08-14 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/blast.rb, lib/bio/appl/blast/genomenet.rb,
              lib/bio/appl/blast/remote.rb

              Bio::Blast#exec_genomenet is moved to genomenet.rb, with bug fix.

              * Bio::Blast#exec_genomenet is moved to
                lib/bio/appl/blast/genomenet.rb.
              * Incompatible change: Bio::Blast#exec_* is changed to return
                String. Parsing the string is now processed in query method.
              * New module Bio::Blast::Remote, to store remote BLAST factories.
              * New module Bio::Blast::Remote::GenomeNet (and Genomenet for
                lazy including), to store exec_genomenet and other methods.
                In the future, it might be a standalone class (or something else).
              * New module methods Bio::Blast::Remote::GenomeNet.databases,
                nucleotide_databases, protein_databases, and database_description,
                to provide information of available databases.
              * Bug fix: remote BLAST on GenomeNet with long query sequences
                fails because of the change of the behavior of the remote site.
              * Incompatible change: Bio::Blast#options= can change program,
                db, format, matrix, and filter instance variables.
              * Bio::Blast#format= is added.
              * Bio::Blast.local changed to accept 4th argument: full path to
                the blastall command.

            * lib/bio/appl/blast/ddbj.rb, lib/bio/io/ddbjxml.rb,
              lib/bio/appl/blast/genomenet.rb, lib/bio/appl/blast/remote.rb,
              lib/bio/appl/blast.rb

              New module Bio::Blast::Remote::DDBJ, remote BLAST on DDBJ.

              * New module Bio::Blast::Remote::DDBJ, remote BLAST routine using
                DDBJ Web API for Biology (WABI). Now, Bio::Blast.new(program,
                db, options, 'ddbj') works.
              * New class Bio::DDBJ::XML::RequestManager. In this class,
                workaround for Ruby 1.8.5's bundled SOAP4R is made.
              * Some common codes are moved from
                Bio::Blast::Remote::GenomeNet::Information to
                Bio::Blast::Remote::Information.

            * lib/bio/io/ddbjxml.rb

              Changed to use DDBJ REST interface for a workaround instead of
              editing WSDL. (commit a64c8da5df5076c5f55b54b7f134d22a2e8d281c)

2008-08-09 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/blast.rb

              * Bug fix: Bio::Blast raises TypeError without "-m" option,
                reported by Natapol Pornputapong.
              * New class Bio::Blast::NCBIOptions to treat command-line options
                for blastall (and for other NCBI tools, e.g. formatdb).
              * Changed not to overwrite @filter, @matrix or @format unless
                '-F', '-M', or '-m' option is given, respectively.

2008-07-30 BioHackathon2008 participants from BioRuby project

            * Branch 'biohackathon2008' is merged.
              See doc/Changes-1.3.rd for incompatible changes.

            * lib/bio/sequence.rb, lib/bio/sequence/
            * lib/bio/db/embl/
            * lib/bio/db/genbank/
            * lib/bio/db/fasta.rb, lib/bio/db/fasta/

              A new method #to_biosequence is added to Bio::EMBL, Bio::GenBank
              and Bio::FastaFormat. Bio::FastaFormat#to_seq is now an alias of
              the #to_biosequence method.

              Bio::Sequence#output is added to output formatted text.
              Supported formats are: EMBL, GenBank, Fasta, or raw.

              Written by Naohisa Goto and Jan Aerts.

            * lib/bio/db/biosql/
            * lib/bio/io/sql.rb, lib/bio/io/biosql/

              New BioSQL implementation by Raoul Jean Pierre Bonnal.

            * lib/bio/reference.rb
            * lib/bio/feature.rb

              Bio::References and Bio::Features are obsoleted.
              For more information, see doc/Changes-1.3.rd.

            * (Many changes are not listed here. See git log for details.)

2008-07-30 Naohisa Goto <ng@bioruby.org>

            * lib/bio/db/gff.rb, test/unit/bio/db/test_gff.rb

              Branch 'test-gff3' in git://github.com/ngoto/bioruby is merged.
              Fixed gff3 attribute bug, and many improvements are added.
              See doc/Changes-1.3.rd for incompatible changes.
              Thanks to Ben Woodcroft who reported the bug and contributed codes.

2008-07-29 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/blast/format0.rb

              Bug fix: fixed ScanError when bit score is in exponential notation
              such as 1.234e+5. Regular expressions for numerics including
              exponential notations are changed to get correct values.

2008-07-18 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/hmmer.rb

              Bug fix: ArgumentError caused by misspelling of a variable name.

2008-06-23 Jan Aerts <jan.aerts@gmail.com>

            * README.rdoc
            * README_DEV.rdoc
            * gemspec.rb

              Renamed README files to RDoc gets parsed on github website.
              (commit 34b7693f74de2358759e955d8ce36cfe15e64b54)
              Edited README.rdoc and README_DEV.rdoc to reflect move from CVS
              to git.
              (commit a61b16163d3ca74f3f7c8d8e8f03f5f8c68dee60)

2008-06-13 Naohisa Goto <ng@bioruby.org>

            * lib/bio/reference.rb
            * test/unit/bio/test_reference.rb

              * New method Bio::Reference#pubmed_url added (renamed the url method
                in CVS revision 1.25).
              * Bio::Reference#endnote is changed not to overwrite url if url is
                already given by user.
              * Improvement of Bio::Reference#bibtex method. (Idea to improve
                bibtex method is originally made by Pjotr Prins.)

            * test/unit/bio/util/restriction_enzyme/double_stranded/test_aligned_strands.rb
              "require 'bio/sequence'" is needed to run the tests in this file.
              (commit 735e3563b723645afa65f0e4213a7c92152f68ec)

2008-05-19 Pjotr Prins <pjotr.prins@wur.nl>

            * sample/fastasort.rb

              Simple example for sorting a flatfile
              (commit 677ac7c0707860f0478e75f72f23faa05b29dc6d)

            * doc/Tutorial.rd
            * sample/fastagrep.rb
            * sample/fastasort.rb

              Piping FASTA files (examples and doc)
              (commit ecd5e04477246dcf6cac84a6fbd21fb59efa3cf0)

2008-05-14 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/blast/format0.rb

              Bug fix: Possibly because of the output format changes of PHI-BLAST,
              Bio::Blast::Default::Report::Iteration#eff_space (and the shortcut
              method in the Report class) failed for PHI-BLAST (blastpgp) results,
              and Iteration#pattern and #pattern_positions (and the
              shortcut methods in the Report class) returned incorrect values.

2008-05-12 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/blast/xmlparser.rb, lib/bio/appl/blast/rexml.rb

              Bug fix: unit test sometime fails due to improper treatment of some
              Blast parameters and difference between rexml and xmlparser.
              To fix the bug, types of some parameters may be changed, e.g.
              Bio::Blast::Report#expect is changed to return Float or nil.

            * lib/bio/appl/blast/format0.rb

              Bug fix: Bio::Blast::Default::Report#eff_space returns wrong value
              ("Effective length of database"). It should return the value of
              "Effective search space".

            * test/unit/bio/appl/blast/test_xmlparser.rb

              Bug fix: tests in test/unit/bio/appl/blast/test_report.rb were
              ignored because of conflicts of the names of test classes.
              Class name in test_xmlparser.rb is changed to fix the bug.

2008-04-23 Naohisa Goto <ng@bioruby.org>

            * lib/bio/db/embl/common.rb

              Bug fix: Bio::EMBL#references failed to parse journal name,
              volume, issue, pages, and year. In addition, it might failed
              to parse PubMed ID.
              (commit c715f51729b115309a78cf29fdce7fef992da875)

2008-04-18 Naohisa Goto <ng@bioruby.org>

            * lib/bio/db/embl/sptr.rb

              Bug fix: Bio::SPTR#references raises NoMethodError since
              lib/bio/db/embl/sptr.rb CVS version 1.34.
              (commit 1b3e484e19c9c547cecfe53858a646b525685e0d)

2008-04-15 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/blast/rpsblast.rb

              Newly added RPS-Blast default (-m 0) output parser.

2008-04-01 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/blast/format0.rb

              Fixed a bug: Failed to parse database name in some cases.
              Thanks to Tomoaki Nishiyama who reported the bug and sent patches
              ([BioRuby-ja] BLAST format0 parser fails header parsing output
              of specific databases).

            * lib/bio/db/pdb/chain.rb, lib/bio/db/pdb/pdb.rb

              Fixed bugs: Bio::PDB::Chain#aaseq failed for nucleotide chain;
              Failed to parse chains for some entries (e.g. 1B2M).
              Thanks to Semin Lee who reported the bugs and sent patches
              ([BioRuby] Bio::PDB parsing problem (1B2M)).

2008-02-19 Toshiaki Katayama <k@bioruby.org>

            * lib/bio/io/ncbirest.rb
            * lib/bio/io/pubmed.rb

              NCBI E-Utilities (REST) functionality is separated to ncbirest.rb
              and pubmed.rb is changed to utilize the Bio::NCBI::REST class for
              esearch and efetch. You can now search and retrieve any database
              in any format that NCBI supports by E-Utilities through the
              Bio::NCBI::REST interface (currently, only esearch and efetch methods
              are implemented).
              (commit 0677bb69044cf6cfba453420bc1bbeb422f691c1)
              (commit f60e9f8153efacff0c97d12fb5c0830ebeb02edd)
              (commit 6e4670ab5e67ca596788f4c26a95a9687d36ce84)

2008-02-13 Pjotr Prins <pjotr.prins@wur.nl>

            * doc/Tutorial.rd
              (commit d7ee01d86d6982f6b8aa19eba9adac95bebb08e8)

2008-02-12 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/blast/format0.rb

              Fixed bugs: Failed to parse query length for long query
              (>= 10000 letters) as comma is inserted for digit separator
              by blastall; Failed to parse e-value for some BLASTX results.
              Thanks to Shuji Shigenobu who reported the bugs and sent patches.

2008-02-11 Pjotr Prins <pjotr.prins@wur.nl>

            * doc/Tutorial.rd

              Expanding on the Tutorial
              (bdc1d14f497909041fa761f659a74d98702a335a)
              Minor adjustments to Tutorial
              (72b5f4f0667a3a0c44ca31b0ab8228381e37919c)

2008-02-06 Pjotr Prins <pjotr.prins@wur.nl>

            * sample/na2aa.rb

              Simple example to translate any NA to AA fasta
              (commit 433f974219cf04342935c1760464af24a5696c49)

2008-02-05 Pjotr Prins <pjotr.prins@wur.nl>

            * sample/gb2fasta.rb

              Fixed broken require in gb2fasta example
              (commit b55daed0d6cff2e45155be01ef2a946925c972cf)

2008-02-05 Pjotr Prins <pjotr.prins@wur.nl>

            * doc/Tutorial.rd

              Minor tweak to Tutorial.rd
              (commit 75416d780f99de24498a47fd22703d74f9a22329)

2008-02-03 Pjotr Prins <pjotr.prins@wur.nl>

            * doc/Tutorial.rd

              More doctests in Tutorial.rd
              (commit 39d182bb67977956c0f22631ac596d65ccce74ff)

2008-02-02 Pjotr Prins <pjotr.prins@wur.nl>

            * doc/Tutorial.rd

              Tabs in the Tutorial broke the rd parser - the Wiki will be fixed
              now.
              (commit 49078a5dea4f16f44add1882c60bf75df67ea19b)
              Updating tutorial.
              (commit f2f2005c3964f37e2d65afef0d52e63950d6bcb7)
              (commit d2b05581953712d0ac67ba0de1aa43853ed4e27f)

2008-02-02 Toshiaki Katayama <k@bioruby.org>

            * lib/bio/shell/rails/vendor/plugins/

              The 'generators' directory is moved under the 'bioruby' subdirectory
              so that 'bioruby --rails' command can work with Rails 2.x series
              in addition to the Rails 1.2.x series.

2008-01-30 Mitsuteru Nakao <n@bioruby.org>

            * lib/bio/appl/blast.rb

              Fixed the bug at building the blastall command line options ('-m 0').
              (commit 61443d177847825505103488573186dfc4e7568e)

2008-01-10 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/emboss.rb

              Added a method Bio::EMBOSS.run(program, arguments...)
              and Bio::EMBOSS.new is obsoleted.
              (commit fa04d97b073aefe05edc34a84498ba0a57ff98d2)

2008-01-10 Toshiaki Katayama <k@bioruby.org>

            * lib/bio/io/hinv.rb

              Bio::Hinv to access the H-invitational DB (http://h-invitational.jp/)
              web service in REST mode is added.

2007-12-30 Toshiaki Katayama <k@bioruby.org>

            * BioRuby 1.2.1 released

              This version is not Ruby 1.9 (released few days ago) compliant yet.

2007-12-28 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/blast/report/format0.rb

              Fixed parse error when compisition-based statistics were enabled.
              In addition, Bio::Blast::Default::Report#references and
              Bio::Blast::Default::Report::HSP#stat_method methods are added.
              In NCBI BLAST 2.2.17, default option of composition-based
              statistics for blastp or tblastn are changed to be enabled
              by default.

            * lib/bio/appl/blast/report/wublast.rb

              Changed to follow the above changes in format0.rb.

            * lib/bio/sequence/common.rb

              Ruby 1.9 compliant: in window_search method, a local variable name
              outside the iterator loop is changed not to be shadowed by the
              iterator variable.

            * lib/bio/db/pdb/pdb.rb

              Ruby 1.9 compliant: changed to avoid "RuntimeError: implicit
              argument passing of super from method defined by define_method()
              is not supported. Specify all arguments explicitly." error.

              Ruby 1.9 compliant: Bio::PDB::Record.get_record_class and
              Bio::PDB::Record.create_definition_hash (Note: they should only
              be internally used by PDB parser and users should not call them)
              are changed to follow the change of Module#constants which
              returns an array of Symbol instead of String.

2007-12-26 Naohisa Goto <ng@bioruby.org>

            * lib/bio/alignment.rb

              Ruby 1.9 compliant: in EnumerableExtension#each_window and
              OriginalAlignment#index methods, local variable names outside the
              iterator loops are changed not to be shadowed by iterator
              variables.

              Warning messages for uninitialized instance variables of
              @gap_regexp, @gap_char, @missing_char, and @seqclass
              are suppressed.

            * test/unit/bio/test_alignment.rb

              Ruby 1.9 compliant: Ruby 1.9 compliant: The last comma in Array.[]
              is no longer allowed. (For example,
                class A < Array; end; A[ 1, 2, 3, ]
              raises syntax error in Ruby 1.9.)

2007-12-21 Toshiaki Katayama <k@bioruby.org>

            * lib/bio/db/medline.rb

              Added doi and pii methods to extract DOI and PII number from AID field

2007-12-18 Naohisa Goto <ng@bioruby.org>

            * lib/bio/db/pdb/pdb.rb

              Bio::PDB#inspect is added to prevent memory exhaust problem.
              ([BioRuby] Parse big PDB use up all memory)

            * lib/bio/db/pdb/model.rb

              Bio::PDB::Model#inspect is added.

            * lib/bio/db/pdb/chain.rb

              Bio::PDB::Chain#inspect is added.

            * lib/bio/db/pdb/residue.rb

              Bio::PDB::Residue#inspect is added.
              This also affects Bio::PDB::Heterogen#inspect.

2007-12-15 Toshiaki Katayama <k@bioruby.org>

            * BioRuby 1.2.0 released

              * BioRuby shell is improved
                * file save functionality is fixed
                * deprecated require_gem is changed to gem to suppress warnings
                * deprecated end_form_tag is rewrited to suppress warnings
                * images for Rails shell are separated to the bioruby directory
                * spinner is shown during the evaluation
                * background image in the textarea is removed for the visibility
              * Bio::Blast is fixed to parse -m 8 formatted result correctly
              * Bio::PubMed is rewrited to enhance its functionality
                * e.g. 'rettype' => 'count' and 'retmode' => 'xml' are available
              * Bio::FlatFile is improved to accept recent MEDLINE format
              * Bio::KEGG::COMPOUND is enhanced to utilize REMARK field
              * Bio::KEGG::API is fixed to skip filter when the value is Fixnum
              * A number of minor bug fixes

2007-12-12 Naohisa Goto <ng@bioruby.org>

            * lib/bio/db/newick.rb:

              Changed to be compliant with the Gary Olsen's Interpretation of
              the "Newick's 8:45" Tree Format Standard.

            * test/unit/bio/db/test_newick.rb

              More tests are added.

            * lib/bio/io/flatfile/indexer.rb

              Fixed a misspelling in Bio::FlatFileIndex.formatstring2class.

2007-11-28 Toshiaki Katayama <k@bioruby.org>

            * lib/bio/io/pubmed.rb:

              Fixed search, query methods (but use of esearch and efetch is
              strongly recommended).

              efetch method is enhanced to accept any PubMed search options
              as a hash (to retrieve in XML format etc.)

              Changed to wait 3 seconds among each access by default to be
              compliant with the NCBI terms (Make no more than one request
              every 3 seconds).

              All Bio::PubMed.* class methods are changed to instance methods
              (interface as the class methods are remained for the backward
              compatibility).

2007-07-19 Toshiaki Katayama <k@bioruby.org>

            * BioRuby 1.1.0 released

2007-07-17 Toshiaki Katayama <k@bioruby.org>

            * lib/bio/io/das.rb

              Fixed that mapmaster method to return correct value (mapmaseter's
              URL). This bug is reported and fixed by Dave Thorne.

2007-07-16 Naohisa Goto <ng@bioruby.org>

            * lib/bio/mafft/report.rb

              For generic multi-fasta formatted sequence alignment,
              Bio::Alignment::MultiFastaFormat is newly added based on
              Bio::MAFFT::Report class, and Bio::MAFFT::Report is
              changed to inherit the new class.
              Tests are added in test/unit/bio/appl/mafft/test_report.rb.

            * lib/bio/alignment.rb

              New modules and classes Bio::Alignment::FactoryTemplate::* are added.
              They are used by following three new classes.

            * lib/bio/appl/muscle.rb
            * lib/bio/appl/probcons.rb
            * lib/bio/appl/tcoffee.rb

              New classess Bio::Muscle, Bio::Probcons, and Bio::Tcoffee are added
              for MUSCLE, ProbCons, and T-Coffee multiple alignment programs.
              Contributed by Jeffrey Blakeslee and colleagues.

            * lib/bio/appl/clustalw.rb
            * lib/bio/appl/mafft.rb

              Interfaces of Bio::ClustalW and Bio::MAFFT are added/modified
              to follow Bio::Alignment::FactoryTemplate (but not yet changed to
              use it).

2007-07-09 Toshiaki Katayama <k@bioruby.org>

            * BioRuby shell on Rails has new CSS theme

              Completely new design for BioRuby shell on Rails translated from
              the 'DibdoltRed' theme on www.openwebdesign.org which is created by
              Darjan Panic and Brian Green as a public domain work!

2007-07-09 Toshiaki Katayama <k@bioruby.org>

            * lib/bio/db/kegg/taxonomy.rb

              Newly added KEGG taxonomy file parser which treats taxonomic tree
              structure of the KEGG organisms. The file is available at
                ftp://ftp.genome.jp/pub/kegg/genes/taxonomy
              and is a replacement of the previously used keggtab file (obsoleted).

            * lib/bio/db/kegg/keggtab.rb

              Bio::KEGG::Keggtab is obsoleted as the file is no longer provided.
              Use Bio::KEGG::Taxonomy (lib/bio/db/kegg/taxonomy.rb) instead.

            * lib/bio/shell/plugin/soap.rb

              Newly added web service plugins for BioRuby shell which supports
              NCBI SOAP, EBI SOAP and DDBJ XML in addition to the KEGG API.

2007-07-09 Naohisa Goto <ng@bioruby.org>

            * lib/bio/db/pdb/pdb.rb

              Pdb_LString.new is changed not to raise error for nil.

              Fixed a bug when below records does not exist in a PDB entry:
              REMARK (remark), JRNL (jrnl), HELIX (helix),
              TURN (turn), SHEET (sheet), SSBOND (ssbond), SEQRES (seqres),
              DBREF (dbref), KEYWDS (keywords), AUTHOR (authors),
              HEADER (entry_id, accession, classification),
              TITLE (definition), and REVDAT (version) records (methods).

              Incompatible change: Bio::PDB#record is changed to return
              an empty array for nonexistent record.

              (reported by Mikael Borg)

2007-07-09 Naohisa Goto <ng@bioruby.org>

            * lib/bio/io/flatfile.rb

              Bio::FlatFile.foreach is added (which is suggested by IO.foreach).

2007-06-28 Toshiaki Katayama <k@bioruby.org>

            * lib/bio/shell/setup.rb, core.rb

              Changed not to use Dir.chdir by caching full path of the save
              directory at a start up time, so that user can freely change
              the work directory without affecting object/history saving
              functionality.

              Bio::Shell.cache[:savedir] stores the session saving directory
              (session means shell/session/{config,history,object} files),
              Bio::Shell.cache[:workdir] stores the working directory at a start
              up time (can be same directory with the :savedir) and both are
              converted and stored as full path allowing user to use Dir.chdir
              in the shell session).

              If --rails (-r) option is applied, 'bioruby' command will run in
              the Rails server mode, and the server will start in the :savedir.

              (A) IRB mode

              1. run in the current directory and the session will be saved
                 in the ~/.bioruby directory

                   % bioruby

              2. run in the current directory and the session will be saved
                 in the foo/bar directory

                   % bioruby foo/bar

              3. run in the current directory and the session will be saved
                 in the /tmp/foo/bar directory

                   % bioruby /tmp/foo/bar

              (B) Rails mode

              4. run in the ~/.bioruby directory and the session will also be saved
                 in the ~/.bioruby directory

                   % bioruby -r

              5. run in the foo/bar directory and the session will also be saved
                 in the foo/bar directory

                   % bioruby -r foo/bar

              6. run in the /tmp/foo/bar directory and the session will also be
                 saved in the /tmp/foo/bar directory

                   % bioruby -r /tmp/foo/bar

              (C) Script mode

              7. run in the current directory using the session saved
                 in the ~/.bioruby directory

                   % bioruby ~/.bioruby/shell/script.rb

              8. run in the current directory using the session saved
                 in the foo/bar directory

                   % bioruby foo/bar/shell/script.rb

              9. run in the current directory using the session saved
                 in the /tmp/foo/bar directory

                   % bioruby /tmp/foo/bar/shell/script.rb

2007-06-21 Toshiaki Katayama <k@bioruby.org>

            * lib/bio/shell/setup.rb

              If no directory is specified to the bioruby command,
              use ~/.bioruby directory as the default save directory
              instead of the current directory, as suggested by Jun Sese.

              User can use 'bioruby' command without botherd by directories
              and files previously created by the 'bioruby' command
              in the current directory even when not needed.

2007-05-19 Toshiaki Katayama <k@bioruby.org>

            * lib/bio/appl/fasta.rb

              Bug fixed that exec_local fails to exec when @ktup is nil.
              This problem is reported and fixed by Fredrik Johansson.

            * lib/bio/db/gff.rb

              parser_attributes method in GFF3 class is modified to use
              '=' char as a separator instead of ' ' (which is used in
              GFF2 spec).

2007-04-06 Toshiaki Katayama <k@bioruby.org>

            * COPYING, COPYING.LIB are removed

              BioRuby is now distributed under the same terms as Ruby.

              On behalf of the BioRuby developer, I have asked all authors of
              the BioRuby code to change BioRuby's license from LGPL to Ruby's.
              And we have finished to change license of all modules in the BioRuby
              library. This means that Ruby user can freely use BioRuby library
              without being annoyed by licensing issues.

            * lib/bio/db/kegg/ko.rb is renamed to lib/bio/db/kegg/ortholog.rb

              KEGG KO database is renamed to KEGG ORTHOLOG database, thus we
              follow the change. Bio::KEGG::KO is renamed to Bio::KEGG::ORTHOLOG.

              Bio::KEGG::ORTHOLOG#genes, dblinks methods are rewrited to use
              lines_fetch method.

            * lib/bio/data/aa.rb

              to_re method is changed that the generated regexp to include
              ambiguous amino acid itself - replacement of amino acid X should
              include X itself.

2007-04-05 Trevor Wennblom <trevor@corevx.com>

            * License headers are completely rewrited to Ruby's.

2007-04-02 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/mafft.rb

              Incompatible change: Bio::MAFFT#output is changed to return
              a string of multi-fasta formmatted text. To get an array of
              Bio::FastaFormat objects (as of 1.0 or before), please use
              report.data instead.

2007-03-29 Toshiaki Katayama <k@bioruby.org>

            * lib/bio/db/kegg/cell.rb

              Obsoleted as the KEGG CELL database is not publically available
              any more.

2007-03-28 Toshiaki Katayama <k@bioruby.org>

            * lib/bio/shell/rails/.../bioruby_controller.rb

              BioRuby shell on Rails access is changed to be limited only from
              the localhost for security reason (if local_request?).

            * lib/bio/command.rb

              The post_form method is modified to accept URL as a string and
              extended to accept params as
                array of string
                array of hash
                array of array
                 or
                string
              in addition to hash (also can be ommited if not needed - defaults
              to nil).

              Keys and parameters of params are forced to use to_s for sure.

            * lib/bio/io/ensembl.rb

              Re-designed to allows user to use Bio::Ensembl.new without
              creating inherited sub class.

              Changed to use Bio::Command.post_form

            * lib/bio/das.rb

              Changed to use Bio::Command

            * lib/bio/shell/plugin/das.rb

              Newly added BioDAS client plugin for BioRuby shell.

                das.list_sequences
                das.dna
                das.features

2007-03-15 Toshiaki Katayama <k@bioruby.org>

            * lib/bio/shell/irb.rb

              Changed to load Rails environment when bioruby shell is invoked
              in the Rails project directory. This means that user can use
              'bioruby' command as a better './script/console' which has
              persistent objects and shared history.

2007-03-08 Toshiaki Katayama <k@bioruby.org>

            * lib/bio/db/kegg/drug.rb

              Newly added KEGG DRUG database parser.

            * lib/bio/db/kegg/glycan.rb

              Bio::KEGG::GLYCAN#bindings method is removed.
              Bio::KEGG::GLYCAN#comment, remarks methods are added.
              Bio::KEGG::GLYCAN#orthologs and dblinks methods are changed to use
              lines_fetch method.

            * lib/bio/kegg/compound.rb

              Bio::KEGG::COMPOUND#glycans method is added
              Bio::KEGG::COMPOUND#names method is changed to return an array
              of stripped strings.

            * lib/bio/db/kegg/genes.rb

              Bio::KEGG::GENES#orthologs method is added.

2007-03-27 Naohisa Goto <ng@bioruby.org>

            * lib/bio/command.rb

              Bio::Command.call_command_fork and query_command_fork methods
              are changed to handle all Ruby exceptions in the child process.

            * lib/bio/io/flatfile.rb

              UniProt format autodetection was changed to follow the change of
              UniProtKB release 9.0 of 31-Oct-2006.

2007-02-12 Naohisa Goto <ng@bioruby.org>

            * lib/bio/io/flatfile.rb

              Exception class UnknownDataFormatError is added.
              It will be raised before reading data from IO when data format
              hasn't been specified due to failure of file format autodetection.

2007-02-12 Toshiaki Katayama <k@bioruby.org>

            * lib/bio/io/flatfile.rb

              Added support for KEGG EGENES.

2007-02-02 Trevor Wennblom <trevor@corevx.com>

            * lib/bio/util/restriction_enzyme*

              Bio::RestrictionEnzyme stabilized.

2007-02-02 Trevor Wennblom <trevor@corevx.com>

            * lib/bio/db/lasergene.rb

              Bio::Lasergene Interface for DNAStar Lasergene sequence file format

2007-02-02 Trevor Wennblom <trevor@corevx.com>

            * lib/bio/db/soft.rb

              Bio::SOFT for reading SOFT formatted NCBI GEO files.

2007-01-16 Toshiaki Katayama <k@bioruby.org>

            * BioRuby shell on Rails new features and fixes

              New features:
              * Input [#] is linked to action for filling textarea from history
              * [methods] is separated into columns for readability

              Fixes and improvements:
              * HIDE_VARIABLES is moved from helper to controller to avoid warning
                "already initialized constant - HIDE_VARIABLES" repeated on reload.
              * <div id="evaluate"> is renamed to "log_#" with number for future
                extention.
              * <div id="log_#"> are inserted in the <div id="logs">

2007-01-15 Toshiaki Katayama <k@bioruby.org>

            * lib/bio/db.rb

              lines_fetch method (internally used various bio/db/*.rb modules)
              is rewrited to concatenate indented sub field.

            * lib/bio/db/kegg/compound.rb

              Bio::KEGG::COMPOUND#comment method which returns contents of
              the COMMENT line is added

            * lib/bio/db/kegg/enzyme.rb

              Bio::KEGG::ENZYME#entry_id is changed to return EC number only.
              Previous version of entry_id method is renamed to entry method
              which returns a "EC x.x.x.x   Enzyme" style string.

              Bio::KEGG::ENZYME#obsolete? method is added which returns boolean
              value (true or false) according to the ENTRY line contains
              a string 'Obsolete' or not.

              Bio::KEGG::ENZYME#all_reac, iubmb_reactions, kegg_reactions methods
              are added to support newly added ALL_REAC field.

              Bio::KEGG::ENZYME#inhibitors and orthologs methods are added.

              Bio::KEGG::ENZYME#substrates, products, inhibitors, cofactors,
              pathways, orthologs, diseases, motifs methods are rewrited to
              utilizes new lines_fetch method in db.rb to process continuous
              sub field.

            * lib/bio/db/kegg/genome.rb

              Bio::KEGG::GENOME#scaffolds, gc, genomemap methods are obsoleted.
              Bio::KEGG::GENOME#distance, data_source, original_db methods are
              added.

2006-12-24 Toshiaki Katayama <k@bioruby.org>

            * bin/bioruby, lib/bio/shell/, lib/bio/shell/rails/
              (lib/bio/shell/rails/vendor/plugins/generators/)

              Web functionallity of the BioRuby shell is completely rewrited
              to utilize generator of the Ruby on Rails. This means we don't
              need to have a copy of the rails installation in our code base
              any more. The shell now run in threads so user does not need
              to run 2 processes as before (drb and webrick). Most importantly,
              the shell is extended to have textarea to input any code and
              the evaluated result is returned with AJAX having various neat
              visual effects.

            * lib/bio.rb

              Extended to have Bio.command where command can be any BioRuby
              shell methods.
                ex. puts Bio.getseq("atgc" * 10).randomize.translate

            * lib/bio/shell/plugin/entry.rb, seq.rb

              seq, ent, obj commands are renamed to getseq, getent, getobj
              respectively. This getseq is also changed to return Bio::Sequence
              with @moltype = Bio::Sequence::NA object instead of Bio::Sequence::NA
              object.

            * lib/bio/db/kegg/kgml.rb

              Some method names are changed to avoid confusion:
              * entry_type is renamed to category (<entry type="">)
              * map is renamed to pathway (<entry map="">)

2006-12-19 Christian Zmasek <czmasek@burnham.org>

            * lib/bio/db/nexus.rb

              Bio::Nexus is newly developed during the Phyloinformatics hackathon.

2006-12-16 Toshiaki Katayama <k@birouby.org>

            * lib/bio/io/sql.rb

              Updated to follow recent BioSQL schema contributed by
              Raoul Jean Pierre Bonnal.

2006-12-15 Mitsuteru Nakao <n@bioruby.org>

            * lib/bio/appl/iprscan/report.rb

              Bio::Iprscan::Report for InterProScan output is newly added.

2006-12-15 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/mafft/report.rb

              Bio::MAFFT::Report#initialize is changed to get a string of
              multi-fasta formmatted text instead of Array.

2006-12-14 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/phylip/alignment.rb

              Phylip format multiple sequence alignment parser class
              Bio::Phylip::PhylipFormat is newly added.

            * lib/bio/appl/phylip/distance_matrix.rb

              Bio::Phylip::DistanceMatrix, a parser for phylip distance matrix
              (generated by dnadist/protdist/restdist programs) is newly added.

            * lib/bio/appl/gcg/msf.rb, lib/bio/appl/gcg/seq.rb

              Bio::GCG::Msf in lib/bio/appl/gcg/msf.rb for GCG MSF multiple
              sequence alignment format parser, and Bio::GCG::Seq in
              lib/bio/appl/gcg/seq.rb for GCG sequence format parser are
              newly added.

            * lib/bio/alignment.rb

              Output of Phylip interleaved/non-interleaved format (.phy),
              Molphy alignment format (.mol), and GCG MSF format (.msf)
              are supported. Bio::Alignment::ClustalWFormatter is removed
              and methods in the module are renamed and moved to
              Bio::Alignment::Output.

            * lib/bio/appl/clustalw.rb, lib/bio/appl/mafft.rb, lib/bio/appl/sim4.rb

              Changed to use Bio::Command instead of Open3.popen3.

2006-12-13 Naohisa Goto <ng@bioruby.org>

            * lib/bio/tree.rb, lib/bio/db/newick.rb

              Bio::PhylogeneticTree is renamed to Bio::Tree, and
              lib/bio/phylogenetictree.rb is renamed to lib/bio/tree.rb.
              NHX (New Hampshire eXtended) parser/writer support are added.

2006-12-13 Toshiaki Katayama <k@bioruby.org>

            * doc/Desing.rd.ja, doc/TODO.rd.ja, doc/BioRuby.rd.ja are obsoletd.

2006-10-05 Naohisa Goto <ng@bioruby.org>

            * lib/bio/db/newick.rb

              Bio::Newick for Newick standard phylogenetic tree parser is
              newly added (contributed by Daniel Amelang).

            * lib/bio/phylogenetictree.rb

              Bio::PhylogeneticTree for phylogenetic tree data structure
              is newly added.

2006-09-19 Toshiaki Katayama <k@bioruby.org>

            * lib/bio/io/soapwsdl.rb
            * lib/bio/io/ebisoap.rb
            * lib/bio/io/ncbisoap.rb

              Newly added web service modules.

            * lib/bio/db/kegg/kgml.rb

              Accessor for the <component> attribute is added.

            * lib/bio/shell/plugin/codon.rb

              Support for Pyrrolysine and Selenocysteine are added in the
              BioRuby shell.

            * lib/bio/sshell/plugin/seq.rb

              sixtrans, skip, step methods are added in the BioRuby shell.
                bioruby> seqtrans(seq)

                bioruby> seq.step(window_size) {|subseq|
                  # do something on subseq
                }

                bioruby> seq.skip(window_sizep, step_size) {|subseq|
                  # do something on subseq
                }

2006-07-26 Toshiaki Katayama <k@bioruby.org>

            * lib/bio/data/aa.rb

              Amino acids J (Xle: I/L), O (Pyl: pyrrolysine) and X (unknown)
              are added (now we have consumed 26 alphabets!).

            * lib/bio/io/fastacmd.rb

              Fixed that new version of fastacmd (in BLAST package) changed
              the option from '-D T' to '-D 1', contributed by the author
              of this module Shuji Shigenobu.

            * lib/bio/shell/plugin/psort.rb

              Newly added BioRuby shell plugin for PSORT

            * lib/bio/shell/plugin/blast.rb

              Newly added BioRuby shell plugin for BLAST search against KEGG GENES

            * lib/bio/db/prosite.rb

              PROSITE#re instance method is added to translate PATTERN of
              the entry to Regexp using PROSITE.pa2re class method.

            * lib/bio/db/kegg/genes.rb

              Bio::KEGG::GENES#keggclass method is renamed to pathway
              Bio::KEGG::GENES#splinks method is removed
              Bio::KEGG::GENES#motifs method is added
              these reflect changes made in the original KEGG GENES database.

              Bio::KEGG::GENES#locations method is added to return Bio::Locations
              Bio::KEGG::GENES#codon_usage is renamed cu_list (returns as Array)
              Bio::KEGG::GENES#cu is renamed to codon_usage (returns as Hash)
              Bio::KEGG::GENES#aalen, nalen methods are changed to return
              the number written in the entry (use seq.length to obtain calculated
              number as before).

            * lib/bio/db/kegg/kgml.rb

              Names of some accessors have been changed (including bug fixes)
              and instance variable @dom is obsoleted. Here's a list of
              incompatible attribute names with KGML tags by this change:
                <entry>
                  :id -> :entry_id
                  :type -> :entry_type
                  names()
                <graphics>
                  :name -> :label
                  :type -> :shape
                <relation>
                  :entry1 -> :node1
                  :entry2 -> :node2
                  :type -> :rel
                <subtype>
                  edge()
                <reaction>
                  :name -> :entry_id
                  :type -> :direction

            * lib/bio/io/das.rb

              Bug fixed that the value of segment.stop was overwritten by
              segment.orientation.

2006-07-14 Naohisa Goto <ng@bioruby.org>

            * lib/bio/command.rb

              Bio::Command::Tools and Bio::Command::NetTools are combined
              and re-constructed into a new Bio::Command module.

              lib/bio/appl/blast.rb, lib/bio/appl/fasta.rb,
              lib/bio/appl/emboss.rb, lib/bio/appl/psort.rb,
              lib/bio/appl/hmmer.rb, lib/bio/db/fantom.rb,
              lib/bio/io/fastacmd.rb, lib/bio/io/fetch.rb,
              lib/bio/io/keggapi.rb, lib/bio/io/pubmed.rb, and
              lib/bio/io/registry.rb are changed to use the new Bio::Command
              instead of old Bio::Command or Net::HTTP.

2006-06-29 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/blat/report.rb

              Bio::BLAT::Report::Hit#milli_bad, #percent_identity, #protein?,
              #score, and #psl_version methods/attributes are newly added,
              and psl files without headers are supported (discussed in
              bioruby-ja ML).

2006-06-27 Naohisa Goto <ng@bioruby.org>

            * lib/bio/sequence/na.rb

              Bio::Sequence::NA#gc_content, #at_content, #gc_skew, #at_skew
              are newly added. Bio::Sequence::NA#gc_percent are changed
              not to raise ZeroDivisionError and returns 0 when given sequence
              is empty.

            * lib/bio/db/pdb/pdb.rb

              Bio::PDB::ATOM#name, #resName, #iCode, #chaarge, #segID, and
              #element are changed to strip whitespaces when initializing.
              Bio::PDB::HETATM is also subject to the above changes.
              (suggested by Mikael Borg)

2006-06-12 Naohisa Goto <ng@bioruby.org>

            * lib/bio/io/flatfile.rb

              Bug fix: Bio::FlatFile.open(klass, filename) didn't work.

2006-05-30 Toshiaki Katayama <k@bioruby.org>

            * lib/bio/io/soapwsdl.rb

              Generic list_methods method which extracts web service methods
              defined in the WSDL file is added.

2006-05-02 Mitsuteru Nakao <n@bioruby.org>

            * lib/bio/appl/pts1.rb

              Bio::PTS1 first commit.

2006-04-30 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/blast/format0.rb

              Bug fix: parse error for hits whose database sequence names
              contain 'Score', and subsequent hits after them would lost
              (reported by Tomoaki NISHIYAMA).

2006-04-14 Mitsuteru Nakao <n@bioruby.org>

            * lib/bio/io/ensembl.rb

              Bio::Ensembl first commit. It is a client class for Ensembl Genome
              Browser.

2006-03-22 Naohisa Goto <ng@bioruby.org>

            * lib/bio/io/flatfile.rb

              Bug fix: Bio::FlatFile raises error for pipes, ARGF, etc.
              The bug also affects bio/appl/mafft.rb, bio/appl/clustalw.rb,
              bio/appl/blast.rb, bio/io/fastacmd.rb, and so on.

              Bio::FlatFile#entry_start_pos and #entry_ended_pos are
              changed to be enabled only when Bio::FlatFile#entry_pos_flag
              is true.

2006-02-27 Toshiaki Katayama <k@bioruby.org>

            * BioRuby 1.0.0 released

2006-02-10 Toshiaki Katayama <k@bioruby.org>

            * BioRuby shell is changed to use session/ directory under the current
              or specified directory to store the session information instead of
              ./.bioruby directory.

2006-02-05 Toshiaki Katayama <k@bioruby.org>

            * License to be changed to Ruby's (not yet completed).

2006-02-01 Trevor Wennblom <trevor@corevx.com>

            * Bio::RestrictionEnzyme first commit for comments.
              * See lib/bio/util/restriction_enzyme.rb and
                test/unit/bio/util/restriction_enzyme

2006-01-28 Toshiaki Katayama <k@bioruby.org>

            * lib/bio/appl/emboss.rb

              EMBOSS USA format is now accepted via seqret/entret commands
              and also utilized in the BioRuby shell (lib/bio/shell.rb,
              plugin/entry.rb, plugin/emboss.rb).

            * lib/bio/io/brdb.rb is removed - unused Bio::BRDB (BioRuby DB)

2006-01-23 Toshiaki Katayama <k@bioruby.org>

            * lib/bio/sequence.rb

              Bio::Sequence is refactored to be a container class for
              any sequence annotations.  Functionality is separared into
              several files under the lib/bio/sequence/ direcotry as
              common.rb, compat.rb, aa.rb, na.rb, format.rb

2006-01-20 Toshiaki Katayama <k@bioruby.org>

            * BioRuby 0.7.1 is released.

2006-01-12 Toshiaki Katayama <k@bioruby.org>

            * lib/bio/db.ra: fixed a bug of the tag_cut method introduced in 0.7.0
              (reported by Alex Gutteridge)

2006-01-04 Naohisa Goto <ng@bioruby.org>

            * Bio::PDB is refactored.  See doc/Changes-0.7 for more details.

2005-12-19 Toshiaki Katayama <k@bioruby.org>

            * BioRuby 0.7.0 is released.

              See doc/Changes-0.7.rd file for major and incompatible changes.

2005-12-19 Naohisa Goto <ng@bioruby.org>

            * lib/bio/db/pdb.rb, lib/bio/db/pdb/pdb.rb, lib/bio/db/pdb/*.rb
              * Many changes have been made.
              * Bio::PDB::FieldDef is removed and Bio::PDB::Record is completely
                changed. Now, Record is changed from hash to Struct, and
                method_missing is no longer used.
              * In the "MODEL" record, model_serial is changed to serial.
              * In any records, record_type is changed to record_name.
              * In most records contains real numbers, changed to return
                float values instead of strings.
              * Pdb_AChar, Pdb_Atom, Pdb_Character, Pdb_Continuation,
                Pdb_Date, Pdb_IDcode, Pdb_Integer, Pdb_LString, Pdb_List,
                Pdb_Real, Pdb_Residue_name, Pdb_SList, Pdb_Specification_list,
                Pdb_String, Pdb_StringRJ and Pdb_SymOP are moved under
                Bio::PDB::DataType.
              * There are more and more changes to be written...

            * lib/bio/db/pdb/atom.rb
              * Bio::PDB::Atom is removed.
                Instead, please use Bio::PDB::Record::ATOM and
                Bio::PDB::Record::HETATM.

2005-12-02 Naohisa Goto <ng:bioruby.org>

            * lib/bio/alignment.rb
              * Old Bio::Alignment class is renamed to
                Bio::Alignment::OriginalAlignment.
                Now, new Bio::Alignment is a module. However,
                you don't mind so much because most of the class methods
                previously existed are defined to delegate to the new
                Bio::Alignment::OriginalAlignment class,
                for keeping backward compatibility.
              * New classes and modules are introduced. Please refer RDoc.
              * each_site and some methods changed to return Bio::Alignment::Site,
                which inherits Array (previously returned Array).
              * consensus_iupac now returns only standard bases
                'a', 'c', 'g', 't', 'm', 'r', 'w', 's', 'y', 'k', 'v',
                'h', 'd', 'b', 'n', or nil (in SiteMethods#consensus_iupac) or
                '?' (or missing_char, in EnumerableExtension#consensus_iupac).
                Note that consensus_iupac now does not return u and invalid
                letters not defined in IUPAC standard even if all bases
                are equal.
              * There are more and more changes to be written...

2005-11-05 Toshiaki Katayama <k@bioruby.org>

            * lib/bio/sequence.rb

              Bio::Sequence.auto(str) method is added which auto detect the
              molecular type of the string and then returns the
              Bio::Sequence::NA or Bio::Sequence::AA object.

              Bio::Sequence#blast and Bio::Sequence#fasta methods are removed.

            * lib/bio/shell/plugin/codon.rb

              Newly added plugin to treat codon table.
              ColoredCodonTable is ported from the codontable.rb

2005-11-01 Toshiaki Katayama <k@bioruby.org>

            * bin/bioruby, lib/bio/shell/

              All methods are changed to private methods to avoid adding them
              in top level binding, which caused many unexpected behaviors,
              as adviced by Koichi Sasada.

              The MIDI plugin is now able to select musical scales.

2005-10-23 Toshiaki Katayama <k@bioruby.org>

            * lib/bio/util/color_scheme

              Newly contributed Bio::ColorScheme

            * lib/bio/db/kegg/kgml.rb

              Newly added KEGG KGML parser.

2005-10-05 Toshiaki Katayama <k@bioruby.org>

            * lib/bio/shell/plugin/midi.rb

              Sequcne to MIDI plugin is contributed by Natsuhiro Ichinose

2005-09-25 Toshiaki Katayama <k@bioruby.org>

            * README.DEV

              Newly added guideline document for the contributors.

            * README

              Updated and added instructions on RubyGems.

2005-09-23 Toshiaki Katayama <k@bioruby.org>

            * bin/bioruby, lib/bio/shell.rb, lib/bio/shell/core.rb,
              lib/bio/shell/session.rb, lib/bio/shell/plugin/seq.rb,
              lib/bio/shell/flatfile.rb, lib/bio/shell/obda.rb

              Newly added BioRuby shell, the command line user interface.
              Try 'bioruby' command in your terminal.

            * doc/Changes-0.7.rd

              Newly added document describing incompatible and important
              changes between the BioRuby 0.6 and 0.7 versions.

            * lib/bio/sequence.rb

              Bio::Sequence.guess, Bio::Sequence#guess methods are added
              which guess the sequence type by following fomula (default
              value for the threshold is 0.9).

                          number of ATGC
              --------------------------------------- > threshold
                number of other chars - number of N

2005-09-10 Naohisa Goto <ng@bioruby.org>

            * lib/bio.rb, lib/bio/appl/blast.rb, lib/bio/appl/blast/format0.rb,
              lib/bio/appl/blast/report.rb, lib/bio/appl/clustalw.rb,
              lib/bio/appl/fasta.rb, lib/bio/appl/fasta/format10.rb,
              lib/bio/appl/hmmer.rb, lib/bio/appl/hmmer/report.rb,
              lib/bio/appl/mafft.rb, lib/bio/appl/psort.rb,
              lib/bio/appl/psort/report.rb, lib/bio/appl/sim4.rb,
              lib/bio/db/genbank/ddbj.rb, lib/bio/io/flatfile/bdb.rb,
              lib/bio/io/flatfile/index.rb, lib/bio/io/flatfile/indexer.rb

              fixed autoload problem

            * lib/bio/appl/blast.rb, lib/bio/appl/blast/report.rb

              Bio::Blast.reports method was moved from lib/bio/appl/blast/report.rb
              to lib/bio/appl/blast.rb for autoload.

2005-08-31 Toshiaki Katayama <k@bioryby.org>

            * BioRuby 0.6.4 is released.

            * doc/KEGG_API.rd

              Newly added English version of the KEGG API manual.

            * lib/bio/aa.rb

              the 'one2name' method introduced in 0.6.3 is fixed and added 'one'
              and 'three' methods as aliases for 'to_1' and 'to_3' methods.

2005-08-31 Naohisa Goto <ng@bioruby.org>

            * removed unused file lib/bio/appl/factory.rb
              (the functionality had been integrated into lib/bio/command.rb)

            * doc/Tutorial.rd

              Newly added an English translation of the Japanese tutorial.

2005-08-16 Naohisa Goto <ng@bioruby.org>

            * lib/bio/command.rb

              Newly added Bio::Command::Tools module.
              Bio::Command::Tools is a collection of useful methods
              for execution of external commands.

            * lib/bio/appl/blast.rb, lib/bio/appl/fasta.rb,
              lib/bio/appl/hmmer.rb, lib/bio/io/fastacmd.rb

              For security reason, shell special characters are escaped.

            * lib/bio/appl/blast.rb, lib/bio/appl/fasta.rb, lib/bio/appl/hmmer.rb

              Options are stored with an array (@options).
              #options and #opions= methods are added.

            * lib/bio/appl/blast.rb, lib/bio/appl/fasta.rb

              Bio::Blast.remote and Bio::Fasta.remote is fixed to work
              with the recent change of the GenomeNet.

2005-08-11 Toshiaki Katayama <k@bioruby.org>

            * Sequence#to_re method to have compatibility with 0.6.2 for RNA

            * Fixed Bio::Fastacmd#fetch to work

            * Bio::Fastacmd and Bio::Bl2seq classes (introduced in 0.6.3) are
              renamed to Bio::Blast::Fastacmd, Bio::Blast::Bl2seq respectively.

2005-08-09 Toshiaki Katayama <k@bioruby.org>

            * BioRuby 0.6.3 is released.

              This version would be the final release to support Ruby 1.6 series
              (as long as no serious bug is found:).

            * lib/bio/util/sirna.rb:

              Newly added method for desing of siRNA, contributed by
              Itoshi Nikaido.  The lib/bio/util/ directory if reserved
              for bioinfomatics algorithms implemented by pure Ruby.

            * lib/bio/io/fastacmd.rb:

              Newly added wrapper for NCBI fastacmd program, contributed by
              Shinji Shigenobu.

            * lib/bio/appl/hmmer/report.rb:

              Bug fixed by Masashi Fujita when the position of sequence
              rarely becomes '-' instead of digits.

2005-08-08 Mitsuteru Nakao <n@bioruby.org>

            * lib/bio/db/embl/sptr.rb:

              Added Bio::SPTR#protein_name and Bio::SPTR#synoyms methods.
              contributed by Luca Pireddu.

              Changed Bio::SPTR#gn, Bio::SPTR#gene_name and
              Bio::SPTR#gene_names methods. contributed by Luca Pireddu.

2005-08-08 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/bl2seq/report.rb:

              Newly added bl2seq (BLAST 2 sequences) output parser.

            * lib/bio/appl/blast/format0.rb:

              Added `self.class::` before F0dbstat.new for bl2seq/report.rb

2005-08-07 Toshiaki Katayama <k@bioruby.org>

            * lib/bio/sequence.rb, lib/bio/data/na.rb, lib/bio/data/aa.rb:

              Bio::NucleicAcid, Bio::AminoAcid classes are refactored to have
              Data module, and this module is included and extended to make
              all methods as both of instance methods and class methods.

              Bio::Sequence::NA and AA classes are rewrited (molecular_weight,
              to_re methods) to use Bio::NucleicAcid.

              Bio::Sequence::NA#molecular_weight method is fixed to subtract
              two hydrogens per each base.

            * lib/bio/db/medline.rb: publication_type (pt) method is added.

2005-08-07 Naohisa Goto <ng@bioruby.org>

            * lib/bio/db/genbank/common.rb:

              Avoid NoMethodError (private method `chomp` called for nil:NilClass)
              when parsing features of

                ftp://ftp.ncbi.nih.gov/genbank/genomes/Bacteria/
                Salmonella_typhimurium_LT2/AE006468.gbk

2005-07-11 Toshiaki Katayama <k@bioruby.org>

            * bin/br_pmfetch.rb:

              Added sort by page option (--sort page)

            * lib/io/higet.rb:

              Newly added Bio::HGC::HiGet class for HiGet SOAP service.

2005-06-28 Toshiaki Katayama <k@bioruby.org>

            * gemspec.rb: newly added RubyGems spec file.

2005-06-21 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/blast/report.rb:

              Newly added support for reading BLAST -m 7 result files
              through Bio::FlatFile by adding
              DELIMITER = "</BlastOutput>\n" to Bio::Blast::Report class.
              (Note that tab-delimited format (-m 8 and -m 9) are not yet
              supported by Bio::FlatFile)

            * lib/bio/io/flatfile.rb:

              Added file format autodetection of BLAST XML format.

2005-06-20 Naohisa Goto <ng@bioruby.org>

            * lib/bio/appl/blast/format0.rb: added 'to_s' to store original entry

2005-04-04 Mitsuteru Nakao <n@bioruby.org>

            * lib/bio/db/go.rb:

              Newly added Bio::GO::External2go class for parsing external2go file.

2005-03-10 Naohisa Goto <ng@bioruby.org>

            * lib/bio/io/flatfile.rb:

              Added file format autodetection of Spidey (Bio::Spidey::Report).

2005-03-10 Naohisa Goto <ng@bioruby.org>

            * lib/bio/io/flatfile.rb:

              Added file format autodetection for Bio::KEGG::KO,
              Bio::KEGG::GLYCAN, Bio::KEGG::REACTION, Bio::Blat::Report
              and Bio::Sim4::Report.

              In order to distinguish Bio::KEGG::REACTION and
              Bio::KEGG::COMPOUND, autodetection regexp. of
              Bio::KEGG::COMPOUND were modified.

2005-02-09 KATAYAMA Toshiaki <k@bioruby.org>

            * lib/bio/db/kegg/genes.rb:

              Added cu method which returns codon usage in Hash for the
              convenience (codon_usage method returns in Array or Fixnum).

2004-12-13 KATAYAMA Toshiaki <k@bioruby.org>

            * BioRuby 0.6.2 released.

            * test/all_tests.rb:

              Unit tests for some classes are newly incorporated by
              Moses Hohman.  You can try it by 'ruby install.rb test'

            * lib/bio/appl/spidey/report.rb:

              Newly added Spidey result parser class.

            * lib/bio/appl/blat/report.rb:

              Newly added BLAT result parser class.

            * fixes and improvements:
              * lib/bio/appl/blast/blast/format0.rb
                * minor fix for the Blast default format parser
              * lib/bio/alignment.rb
                * Alignment class
              * lib/bio/db/prosite.rb
                * bug reported by Rolv Seehuus is fixed
                * some methods are added

2004-10-25 KATAYAMA Toshiaki <k@bioruby.org>

            * lib/bio/db/{compound.rb,reaction.rb,glycan.rb}:

              Newly added parser for KEGG REACTION and KEGG GLYCAN database
              entries, fix for KEGG COMPOUND parser to support the new format.

2004-10-09 GOTO Naohisa <ng@bioruby.org>

            * lib/bio/appl/sim4.rb

              Newly added sim4 wrapper class.
              This is test version, specs would be changed frequently.

            * lib/bio/appl/sim4/report.rb

              Newly added sim4 result parser class.

2004-08-25 KATAYAMA Toshiaki <k@bioruby.org>

            * BioRuby 0.6.1 released.
              * fix for the packaging miss of 0.6.0
              * bin/*.rb are renamed to bin/br_*.rb (similar to the BioPerl's
                convention: bp_*.pl)

2004-08-24 KATAYAMA Toshiaki <k@bioruby.org>

            * BioRuby 0.6.0 released.
              * many fixes for Ruby 1.8
              * updated for genome.ad.jp -> genome.jp transition

            * lib/bio/db/pdb.rb

              Newly added parser for PDB contributed by Alex Gutteridge (EBI).

            * lib/bio/data/codontable.rb

              Bio::CodonTable is rewrited to be a class instead of static variable.
              Now it can hold table definition, start codons, stop codons and
              added methods to detect start/stop codons and reverse translation.

              Also includes sample code to show codon table in ANSI colored
              ascii art, have fun.

            * lib/bio/sequence.rb

              Bio::Sequence::NA#translate is rewrited to accept an user defined
              codon table as a Bio::CodonTable object and any character can be
              specified for the unknown codon.  This method runs about 30% faster
              than ever before.

              Bio::Sequence::AA#to_re method is added for the symmetry.

              Bio::Seq will be changed to hold generic rich sequence features.
              This means Bio::Seq is no longer an alias of Bio::Sequence but
              is a sequence object model, something like contents of a GenBank
              entry, common in BioPerl, BioJava etc.

            * lib/bio/io/soapwsdl.rb

              Newly added common interface for SOAP/WSDL in BioRuby
              used by keggapi.rb, ddbjxml.rb.

            * lib/bio/io/keggapi.rb

              Completely rewrited to support KEGG API v3.0

            * lib/bio/io/esoap.rb

              Newly added client library for Entrez Utilities SOAP interface.

            * lib/bio/db/genbank, lib/bio/db/embl

              Refactored to use common.rb as a common module.

            * bin/pmfetch.rb

              Newly added command to search PubMed.

            * bin/biofetch.rb, flatfile.rb, biogetseq.rb

              Renamed to have .rb suffix.

            * sample/biofetch.rb

              Rewrited to use KEGG API instead of DBGET

2003-10-13 KATAYAMA Toshiaki <k@bioruby.org>

            * BioRuby 0.5.3 released.

              Fixed bugs in Blast XML parsers: xmlparser.rb is fixed not to
              omit the string after ' and " in sequence definitions,
              rexml.rb is fixed not to raise NoMethodError as "undefined
              method `each_element_with_text' for nil:NilClass".

2003-10-07 GOTO Naohisa <ngoto@gen-info.osaka-u.ac.jp>

            * lib/bio/db/nbrf.rb

              Newly added NBRF/PIR flatfile sequence format class.

2003-09-30 GOTO Naohisa <ngoto@gen-info.osaka-u.ac.jp>

            * lib/bio/db/pdb.rb

              Newly added PDB database flatfile format class.
              This is pre-alpha version, specs shall be changed frequently.

2003-08-22 KATAYAMA Toshiaki <k@bioruby.org>

            * BioRuby 0.5.2 released.

              Fixed to be loaded in Ruby 1.8.0 without warnings.

            * doc/KEGG_API.rd.ja

              Newly added a Japanese document on the KEGG API.

2003-08-12 GOTO Naohisa <ngoto@gen-info.osaka-u.ac.jp>

            * lib/bio/appl/blast/format0.rb

              Newly added NCBI BLAST default (-m 0) output parser,
              which may be 5-10x faster than BioPerl's parser.
              This is alpha version, specs may be frequently changed.
              PHI-BLAST support is still incomplete.
              Ruby 1.8 recommended. In ruby 1.6, you need strscan.

            * lib/bio/appl/blast/wublast.rb

              Newly added WU-BLAST default output parser.
              This is alpha version, specs may be frequently changed.
              Support for parameters and statistics are still incomplete.
              Ruby 1.8 recommended. In ruby 1.6, you need strscan.

2003-07-25 GOTO Naohisa <ngoto@gen-info.osaka-u.ac.jp>

            * lib/bio/alignment.rb:

              Newly added multiple sequence alignment class.

            * lib/bio/appl/alignfactory.rb:

              Newly added template class for multiple alignment software.

            * lib/bio/appl/clustalw.rb:

              Newly added CLUSTAL W wrapper.
              <http://www.ebk.ac.uk/clustalw/>
              <ftp://ftp.ebk.ac.uk/pub/software/unix/clustalw/>

            * lib/bio/appl/clustalw/report.rb:

              Newly added CLUSTAL W result data (*.aln file) parser.

            * lib/bio/appl/mafft.rb, lib/bio/appl/mafft/report.rb:

              Newly added MAFFT wrapper and report parser.
              (MAFFT is a multiple sequence alignment program based on FFT.)
              <http://www.biophys.kyoto-u.ac.jp/~katoh/programs/align/mafft/>

2003-07-16 KATAYAMA Toshiaki <k@bioruby.org>

            * BioRuby version 0.5.1 released.

            * lib/bio/sequence.rb: some methods (using 'rna?' internally) were
              temporally unusable by the changes in 0.5.0 is fixed.

            * lib/bio/io/flatfile.rb: autodetection failure of the fasta entry
              without sequence is fixed.  FlatFile.auto method is added.

            * lib/bio/db.rb: sugtag2array fixed.  DB.open now accepts IO/ARGF.

            * lib/bio/db/embl.rb: references method is added.

2003-06-25 KATAYAMA Toshiaki <k@bioruby.org>

            * BioRuby version 0.5.0 released.

            * lib/bio/appl/blast/report.rb:

                Refactored from xmlparser.rb, rexml.rb, and format8.rb files.
                Formats are auto detected and parsers are automatically
                selected by checking whether XMLParser or REXML are installed.
                You can call simply as
                  Bio::Blast::Report.new(blastoutput)
                or you can choose parsers/format explicitly by
                  Bio::Blast::Report.xmlparser(format7blastoutput)
                  Bio::Blast::Report.rexml(fomat7blastoutput)
                  Bio::Blast::Report.tab(format8blastoutput)
                You can also use newly added class method reports for multiple
                xml blast output.
                  Bio::Blast.reports(output) # output can be IO or String

            * lib/bio/appl/fasta/report.rb:

                Refactored from format10.rb, format6.rb and sample/* files.

            * lib/bio/appl/hmmer/report.rb:

                Bug fix and clean up.

            * bin/biogetseq:

                Newly added OBDA (BioRegistry) entry retrieval command.

            * etc/bioinformatics/seqdatabase.ini, lib/bio/io/registry.rb:
                Updated for new OBDA spec (Singapore version).
                Including config file versioning and changes in tag names,
                support for OBDA_SEARCH_PATH environmental variable.

            * lib/bio/io/keggapi.rb:

                Newly added KEGG API client library.
                <http://www.genome.ad.jp/kegg/soap/>

            * lib/bio/io/ddbjxml.rb:

                Newly added DDBJ XML client library (test needed).
                <http://xml.nig.ac.jp/>

            * lib/bio/io/das.rb:

                Newly added BioDAS client library.

            * lib/bio/db/gff.rb:

                Newly added GFF format parser/store library.

            * lib/bio/appl/tmhmm/report.rb:

                Newly added TMHMM report parser.
                <http://www.cbs.dtu.dk/services/TMHMM/>

            * lib/bio/appl/targetp/report.rb:

                Newly added TargetP report parser.
                <http://www.cbs.dtu.dk/services/TargetP/>

            * lib/bio/appl/sosui/report.rb:

                Newly added SOSUI report parser.
                <http://sosui.proteome.bio.tuat.ac.jp/cgi-bin/sosui.cgi>

            * lib/bio/appl/psort/report.rb:

                Newly added PSORT report parser.
                <http://www.psort.org/>, <http://psort.ims.u-tokyo.ac.jp/>

            * lib/bio/appl/genscan/report.rb:

                Newly added GENSCAN report parser.
                <http://genes.mit.edu/GENSCAN.html>

            * lib/bio/db/prosite.rb: bug fix in ps2re method.

            * lib/bio/db/fantom.rb:

                Newly added FANTOM database parser (XML).
                <http://fantom2.gsc.riken.go.jp/>

            * lib/bio/db/go.rb:

                Newly added GO parser.
                <http://www.geneontology.org/>

            * lib/bio/feature.rb:

                'each' method now accepts an argument to select specific feature.

            * lib/bio/db/fasta.rb: definition=, data= to change comment line.

            * lib/bio/db/genbank.rb:

                References and features now accept a block. 'acc_version' method
                is added to return the Accsession.Version string.
                'accession' method now returns Accession part of the acc_version.
                'version' method now returns Version part of the acc_version as
                an integer.

            * lib/bio/db/keggtab.rb:

                Rewrited for bug fix and clean up (note: some methods renamed!)
                * gsub('abrev', 'abbrev') in method names
                * db_path_by_keggorg is changed to db_path_by_abbrev
                * @bio_root is changed to @bioroot (ENV['BIOROOT'] overrides)
                * Bio::KEGG::DBname is changed to Bio::KEGG::Keggtab::DB
                  * @database is added (a hash with its key db_abbreb)
                  * database, name, path methods added with its argument db_abbreb

            * lib/bio/io/flatfile.rb:

               Enumerable mix-in is included.

            * lib/bio/io/flatfile/indexer.rb:

                Indexing of the FASTA format file is now supported with various
                type of definition line.

            * bin/dbget:

                Removed (moved under sample directory because the port of the
                dbget server is now closed).

            * install.rb:

                Changed to use setup 3.1.4 to avoid installing CVS/ directory.

            * sample/goslim.rb:

                Added a sample to generate histogram from GO slim.

            * sample/tdiary.rb:

                Added for tDiary <http://www.tdiary.org/> users. have fun. :)

2003-01-28 KATAYAMA Toshiaki <k@bioruby.org>

            * BioRuby version 0.4.0 released.
            * bin/bioflat:
              * newly added for the BioFlat indexing
            * lib/bio/io/flatfile.rb, flatfile/{indexer.rb,index.rb,bdb.rb}:
              * flatfile indexing is supported by N. Goto
            * lib/bio/db/genbank.rb: changed to contain common methods only
              * lib/bio/db/genbank/genbank.rb
              * lib/bio/db/genbank/genpept.rb
              * lib/bio/db/genbank/refseq.rb
              * lib/bio/db/genbank/ddbj.rb
            * lib/bio/db/embl.rb: changed to contain common methods only
              * lib/bio/db/embl/embl.rb
              * lib/bio/db/embl/sptr.rb
              * lib/bio/db/embl/swissprot.rb
              * lib/bio/db/embl/trembl.rb
            * lib/bio/appl/emboss.rb:
              * added - just a generic wrapper, no specific parsers yet.
            * lib/bio/appl/hmmer.rb:
              * added - execution wrapper
            * lib/bio/appl/hmmer/report.rb:
              * added - parsers for hmmsearch, hmmpfam contributed by H. Suga
            * lib/bio/db.rb: open method added for easy use of flatfile.
            * lib/bio/db/kegg/genes.rb:
              * fixed bug in codon_usage method in the case of long sequence >999
              * eclinks, splinks, pathways, gbposition, chromosome methods added
            * lib/bio/db/aaindex.rb:
              * adapted for the new AAindex2 format (release >= 6.0).
            * lib/bio/db/fasta.rb: entry_id is changed to return first word        only
            * lib/bio/data/na.rb, aa.rb, keggorg.rb:
              * moved under class NucleicAcid, AminoAcid, KEGG (!)
            * in the test codes, DBGET is replaced by BioFetch

2002-08-30 Yoshinori K. Okuji <okuji@enbug.org>

            * lib/bio/matrix.rb: Removed.
            * lib/bio/db/aaindex.rb: Require matrix instead of bio/matrix.
            * lib/bio/db/transfac.rb: Likewise.
            * lib/bio/pathway.rb: Likewise.
              (Pathway#dump_matrix): Don't use Matrix#dump.

2002-07-30 KATAYAMA Toshiaki <k@bioruby.org>

            * BioRuby version 0.3.9 released.
            * lib/bio/location.rb:
              * Locations#length (size) methods added (contributed by N. Goto)
              * Locations#relative method added  (contributed by N. Goto)
              * Locations#absolute method is renamed from offset
              * Locations#offset, offset_aa methods removed
                * use absolute/relative(n, :aa) for _aa
              * Locations#[], range methods added
              * Location#range method added
            * lib/bio/db/embl.rb:
              * fix accession method.
            * lib/bio/db/genpept.rb:
              * temporally added - in the next release, we will make refactoring.
            * lib/bio/reference.rb:
              * in bibtex and bibitem format, "PMIDnum" is changed to "PMID:num".
            * lib/bio/io/pubmed.rb:
              * esearch, efetch methods are added.
            * lib/bio/db/aaindex.rb:
              * fix serious bug in the index method to support negative values.
            * lib/bio/db.rb:
              * fix fetch method to cut tag without fail.
            * lib/bio/extend.rb:
              * added first_line_only option for the prefix in fill method.
            * doc/Tutorial.rd.ja:
              * added docs on BibTeX etc.

2002-06-26 KATAYAMA Toshiaki <k@bioruby.org>

            * BioRuby version 0.3.8 released.
            * lib/bio/sequence.rb:
              * normalize! method added for clean up the object itself.
              * 'to_seq' method was renamed to 'seq' (!)
                * to_xxxx should be used when the class of the object changes.
            * lib/bio/appl/blast/xmparser.rb:
              * each_iteration, each_hit, each, hits, statistics, message methods
                are added in Report class.
              * statistics, message methods are added in Iteration class.
              * methods compatible with Fasta::Report::Hit are added in Hit class.
            * lib/bio/appl/blast/rexml.rb:
              * many APIs were changed to follow the xmlparser.rb's. (!)
            * lib/bio/appl/{blast.rb,fasta.rb]:
              * class method parser() is added for loading specified Report class.
            * etc/bioinformatics/seqdatabase.ini: added for OBDA (!)
              * sample setup for BioRegistry - Open Bio Sequence Database Access.
            * lib/bio/extend.rb: added (!)
              * This module adds some functionarity to the existing classes and
                not loaded by default. User should require specifically if needed.
            * lib/bio/util/*: removed and merged into lib/bio/extend.rb (!)
            * lib/bio/id.rb: removed (!)
            * lib/bio/db/{embl.rb,sptr.rb,transfac.rb}: added entry_id
            * lib/bio/data/keggorg.rb: updated
            * sample/genes2* sample/genome2*: updated
            * doc/Tutrial.rd.ja: updated

2002-06-19 KATAYAMA Toshiaki <k@bioruby.org>

            * BioRuby version 0.3.7 released.
            * lib/bio/sequence.rb: Sequence inherits String again (!)
            * lib/bio/db.rb, db/embl.rb, db/sptr.rb: moved EMBL specific methods

2002-06-18 KATAYAMA Toshiaki <k@bioruby.org>

            * lib/bio/feature.rb: Bio::Feature#[] method added
            * doc/Tutrial.rd.ja: changed to use Feature class

2002-05-28 KATAYAMA Toshiaki <k@bioruby.org>

            * lib/bio/appl/fasta.rb: parser separated, API renewal (!)
              * lib/bio/appl/fasta/format10.rb: moved from fasta.rb

            * lib/bio/appl/blast.rb: parser separated, API renewal (!)
              * lib/bio/appl/blast/format8.rb: newly added
              * lib/bio/appl/blast/rexml.rb: newly added
              * lib/bio/appl/blast/xmlparser.rb: moved from blast.rb

2002-05-16 KATAYAMA Toshiaki <k@bioruby.org>

            * lib/bio/sequence.rb: added alias 'Seq' for class Sequence
            * lib/bio/db/fasta.rb: entry method added

2002-05-15 KATAYAMA Toshiaki <k@bioruby.org>

            * lib/bio/io/dbget.rb: bug fixed for pfam (was wrongly skip # lines)
            * lib/bio/location.rb: offset method added, eased range check

2002-04-26 KATAYAMA Toshiaki <k@bioruby.org>

            * sample/biofetch.rb: new 'info=' option added

2002-04-22 KATAYAMA Toshiaki <k@bioruby.org>

            * lib/bio/appl/fasta.rb: follow changes made at fasta.genome.ad.jp
            * sample/gb2tab.rb: fixed to use authors.inspect for reference

2002-04-15 KATAYAMA Toshiaki <k@bioruby.org>

            * sample/gb2fasta.rb: changed to follow new genbank.rb spec.
            * sample/gt2fasta.rb: changed to follow new genbank.rb spec.
            * sample/gbtab2mysql.rb: added for loading tab delimited data.

2002/04/08

            * version 0.3.6 released -k
              * fixed inconsistency among db.rb, genbank.rb, genome.rb -k
              * lib/bio/db/genbank.rb : serious bug fixed in locus method -k
              * lib/bio/feature.rb : method name 'type' has changed -k

2002/03/27

            * sample/gb2tab.rb changed to follow new genbank.rb w/ new schema -k

2002/03/26

            * sample/gb2tab.rb use ruby instead of perl in the example -o
            * sample/gb2fasta.rb updated -o

2002/03/11

            * version 0.3.5 released -k

2002/03/04

            * lib/bio/sequence.rb to_a, to_ary methods renamed to names, codes -k
            * sample/biofetch.rb added for BioFetch server -k
            * bin/biofetch added for BioFetch client -k
            * lib/bio/io/fetch.rb added for BioFetch library -k
            * lib/bio/io/sql.rb added for BioSQL -k
            * lib/bio/io/registry.rb added for BioDirectory/Registry -k
            * lib/bio/feature.rb added for BioSQL, GenBank, EMBL etc. -k
            * lib/bio/db/genbank.rb rewrited to use Features, References -k
            * lib/bio/db/{genes,genome}.rb clean up -k
            * lib/bio/reference.rb added class References -k

2002/02/05

            * changed to use 'cgi' instead of 'cgi-lib' -n,k

2002/01/31

            * version 0.3.4 released -k
              * lib/bio/db/genbank.rb -k
                * fix for multiple 'allele' in the feature key. (thanx Lixin)

2002/01/07

            * lib/bio/appl/blast.rb -n
              * remote blast support etc.

2001/12/18

            * lib/bio/id.rb -k
              * newly created
            * lib/bio/io/brdb.rb -k
              * newly created
            * lib/bio/db.rb -k
              * template methods are deleted
              * detailed docuement added
            * lib/bio/sequence.rb -k
              * to_fasta, complement, translate fixed (due to the changes made
                in 0.3.3)
              * Sequence::NA#initialize doesn't replace 'u' with 't' any longer
                * gc_percent, complement, translate, to_re, molecular_weight
                  methods are adapted to this change
              * molecular_weight changed to calculate more precisely
              * test code added
            * lib/bio.rb -k
              * rescue for require 'bio/appl/blast' is deleted

2001/12/15

            * lib/bio/sequence.rb -o
              * Sequence#to_str added

2001/12/15

            * version 0.3.3 released -k

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